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Observer agreement for diagnosis of colorectal lesions with analysis of the vascular pattern by image-enhanced endoscopy

机译:影像学内窥镜分析血管形态诊断大肠病变的观察者协议

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Background/Aims: Image-enhanced endoscopy (IEE) can differentiate neoplastic from non-neoplastic colorectal lesions through indirect analysis of pit patterns and microvascular architecture. We evaluated the accuracy of Flexible Spectral Imaging Color Enhancement (FICE) in differentiating neoplastic from non-neoplastic lesions and observer agreement in the analysis of capillary pattern of colorectal lesions. Methods: A prospective double-blind trial was conducted in two referral endoscopy centers. Vascular pattern was analyzed by IEE with magnification. Lesions were divided into two groups and examined separately by two experts. Examiners, blinded to each other’s interpretations, switched groups and the lesions were reviewed. After 60 days, lesions were reevaluated. Results: In total, 76 patients were referred to colonoscopy for colon cancer screening. Of 100 colorectal lesions, 88 were neoplastic (73 tubular adenomas, 10 tubulovillous adenomas, 1 villous adenoma, 2 serrated adenomas, 2 adenocarcinomas) and 12 were non-neoplastic (hyperplastic polyps). Mean diameter of the lesions was 6.7?mm. Examiners 1 and 2 had 95?% accuracy. The interobserver kappa coefficient was 0.80 and the intraobserver kappa coefficient was 0.88 for examiner 1 and 0.73 for examiner 2. Conclusion: IEE with magnification is effective for real-time predictive histological diagnosis of colorectal lesions, with inter- and intraobserver agreement ranging from good to excellent.
机译:背景/目的:图像增强内窥镜检查(IEE)可以通过对凹坑模式和微血管结构进行间接分析,将肿瘤性和非肿瘤性结直肠病变区分开。我们评估了柔性光谱成像色彩增强(FICE)在区分赘生物与非赘生物病变方面的准确性,并评估了结肠直肠病变的毛细血管形态中观察者的同意。方法:在两个转诊内窥镜中心进行了一项前瞻性双盲试验。通过IEE放大分析血管模式。病变分为两组,由两名专家分别检查。检查者对彼此的解释不了解,切换了组并检查了病变。 60天后,重新评估病灶。结果:总共76例患者接受了结肠镜检查以筛查结肠癌。在100个大肠病变中,有88个是肿瘤性的(73个管状腺瘤,10个微管腺瘤,1个绒毛状腺瘤,2个锯齿状腺瘤,2个腺癌)和12个是非肿瘤性(增生性息肉)。病变平均直径为6.7?mm。检验员1和2的准确率达到95%。检验者1的观察者间κ系数为0.80,检验者2的观察者内κ系数为0.88,检验者2的观察者内κ系数为0.73。结论:放大的IEE对于结直肠病变的实时预测组织学诊断是有效的,观察者间和观察者之间的一致性从良好到良好优秀。

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