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首页> 外文期刊>Endoscopy International Open >Correlation of the location of superficial Barrett’s esophageal adenocarcinoma (s-BEA) with the direction of gastroesophageal reflux
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Correlation of the location of superficial Barrett’s esophageal adenocarcinoma (s-BEA) with the direction of gastroesophageal reflux

机译：浅表巴雷特食管腺癌（s-BEA）的位置与胃食管反流方向的相关性

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Background: Superficial Barrett’s esophageal adenocarcinoma (s-BEA) in Barrett’s esophagus frequently occurs in the right wall of the esophagus. Our aim was to examine the correlation between the location of s-BEA and the direction of acid and non-acid reflux in patients with Barrett’s esophagus. Patients and methods: We performed 24-h pH monitoring in 33 s-BEA patients using a pH catheter with eight sensors. One sensor was located at the 6 o’clock position in the lower esophagus and sensors 1?–?8 were arranged counterclockwise at the same level. The catheter was positioned at the same level as the s-BEA. We measured the maximal total duration of acid (MTD-A) and non-acid (MTD-NA) reflux. When the direction of MTD-A and MTD-NA coincided with the location of the s-BEA, the case was defined as coincidental and we calculated the rate of coincidence, and the probability of the rate of coincidence was estimated with 95?% confidence intervals (95?%CI). Results: Among the 33 cases of s-BEA examined, the rate of coincidence of both MTD-A and MTD-NA was 24/33 (72.7?%) (95?%CI 0.54?–?0.87). The rate of coincidence of either MTD-A or MTD-NA was 30/33 (90.9?%) (95?%CI 0.76?–?0.98). Conclusions: Our study revealed that the location of s-BEA mostly corresponds to the direction of MTD-A or MTD-NA. Accurate observation of the distribution of acid or non-acid reflux by pH monitoring would aid early detection of s-BEA by endoscopy.
机译：背景：巴雷特食管中的浅表巴雷特食管腺癌（s-BEA）经常发生在食管的右壁。我们的目的是检查Barrett食管患者s-BEA的位置与酸和非酸反流方向之间的相关性。患者和方法：我们使用具有八个传感器的pH导管对33 s-BEA患者进行了24小时pH监测。一个传感器位于食道下部的6点钟位置，传感器1-8沿逆时针方向设置在同一高度。将导管放置在与s-BEA相同的位置。我们测量了酸（MTD-A）和非酸（MTD-NA）回流的最大总持续时间。当MTD-A和MTD-NA的方向与s-BEA的位置重合时，将情况定义为巧合，我们计算了重合率，估计重合率的概率为95％置信度间隔（95 %% CI）。结果：在检查的33例s-BEA病例中，MTD-A和MTD-NA的重合率为24/33（72.7％）（95％CI 0.54？-？0.87）。 MTD-A或MTD-NA的重合率为30/33（90.9％）（95％CI 0.76？-？0.98）。结论：我们的研究表明，s-BEA的位置主要与MTD-A或MTD-NA的方向相对应。通过pH监测准确观察酸或非酸回流的分布将有助于通过内窥镜检查早期发现s-BEA。

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