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首页> 外文期刊>Endocrine journal >Should we use ultrasound features associated with papillary thyroid cancer in diagnosing medullary thyroid cancer?
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Should we use ultrasound features associated with papillary thyroid cancer in diagnosing medullary thyroid cancer?

机译：在甲状腺髓样癌中，是否应使用与甲状腺乳头状癌相关的超声特征？

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References(21) Cited-By(11) In thyroid nodule management, ultrasound (US) features, such as hypoechogenicity of the lesion, irregular margins, microcalcifications, and intralesional vascular signal, alone or combined, have to be considered as suggestive for malignancy. Because of the low prevalence of medullary thyroid cancer (MTC), a few papers analyzed US characteristics associated with this cancer in small series, with controversial results. Aim of this study was to evaluate in MTC the US risk factors of thyroid nodule. In this order, a series of nodules histologically proven as MTC and a group of nodules with histology of papillary cancer (PTC) were retrospectively compared with a control group of benign nodule. Fifty percent MTC were solid hypoechoic and 16% showed microcalcifications with significant difference with respect to the benign group (pp<0.001) more frequent in PTC than in benign group or MTC series. This study showed low frequency of ultrasound features associated to PTC when analyzed in medullary cancer. Because of the poor literature focusing on this topic, and the herein used design, these data contribute to the knowledge about presentation of MTC at US. We advice for further prospective studies on larger series to define the US presentation of this cancer type.
机译：参考文献（21）被引用（11）在甲状腺结节管理中，超声（美国）功能（例如病变的回弹性降低，边缘不规则，微钙化和病变内血管信号）（单独或组合使用）必须被视为提示恶性肿瘤。由于甲状腺髓样癌（MTC）的患病率较低，因此有几篇论文以小系列分析了与该癌相关的美国特征，并引起了争议。这项研究的目的是在MTC中评估甲状腺结节的美国危险因素。依此顺序，将一系列在组织学上被证实为MTC的结节和一组在乳头状癌（PTC）组织学中的结节与对照组的良性结节进行了比较。 50％的MTC为固体低回声，而16％的PTC患者的微钙化相对于良性组（pp <0.001）的发生率明显高于良性组或MTC系列。这项研究表明，在髓样癌中进行分析时，与PTC相关的超声特征的频率较低。由于针对该主题的文献不多，而且本文使用的设计也很少，因此这些数据有助于了解美国的MTC。我们建议对更大的系列进行进一步的前瞻性研究，以定义这种癌症类型在美国的表现。

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