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首页> 外文期刊>Endocrine journal >Nesidioblastosis in an Adult with Hyperinsulinemic Hypoglycemia
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Nesidioblastosis in an Adult with Hyperinsulinemic Hypoglycemia

机译：成年高胰岛素血症性低血糖的成神经细胞病

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References(9) Cited-By(8) A 50-year-old Korean man with repeated episodes of temporary loss of consciousness was diagnosed as having hyperinsulinemic hypoglycemia. Under the tentative diagnosis of insulinoma, localization procedures were carried out but no tumor was found. By percutaneous transhepatic portal venous sampling, no definite gradient in insulin concentration was found. During exploratory laparotomy no tumor was palpable in the pancreas, and intraoperative ultrasonography showed low echogenicity in the pancreatic head. Whipple's operation was performed and 70% of the proximal pancreas was removed. Histomorphometric examination of the resected specimen revealed graded hyperplasia of the islet cells. The most profuse hyperplasia was noted in the head with progressive decrease in the degree of hyperplasia to the body and tail. The patient remains euglycemic and tolerates 24h fasting without any medication until 15 months after operation.
机译：参考文献（9）被引（8）一名50岁的韩国男子反复出现暂时性意识丧失，被诊断为高胰岛素血症性低血糖症。在胰岛素瘤的初步诊断下，进行了定位程序，但未发现肿瘤。通过经皮肝门静脉取样，未发现胰岛素浓度的确定梯度。在探索性剖腹手术中，胰腺未触及肿瘤，术中超声检查显示胰头回声低。进行了Whipple手术，并切除了近端胰腺的70％。切除标本的组织形态计量学检查显示了胰岛细胞的分级增生。头部中最丰富的增生表现为身体和尾巴的增生程度逐渐降低。患者保持血糖正常，并且在手术后15个月内无需任何药物即可耐受24小时的空腹。

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