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首页> 外文期刊>Environmental Health: A Global Access Science Source >Influence of mercury exposure on blood pressure, resting heart rate and heart rate variability in French Polynesians: a cross-sectional study
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Influence of mercury exposure on blood pressure, resting heart rate and heart rate variability in French Polynesians: a cross-sectional study

机译：汞暴露对法属波利尼西亚人的血压，静息心率和心率变异性的影响：一项横断面研究

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Background Populations which diet is rich in seafood are highly exposed to contaminants such as mercury, which could affect cardiovascular risk factors Objective To assess the associations between mercury and blood pressure (BP), resting heart rate (HR) and HR variability (HRV) among French Polynesians Methods Data were collected among 180 adults (≥ 18 years) and 101 teenagers (12-17 years). HRV was measured using a two-hour ambulatory electrocardiogram (Holter) and BP was measured using a standardized protocol. The association between mercury and HRV and BP parameters was studied using analysis of variance (ANOVA) and analysis of covariance (ANCOVA) Results Among teenagers, the high frequency (HF) decreased between the 2nd and 3rd tertile (380 vs. 204 ms2, p = 0.03) and a similar pattern was observed for the square root of the mean squared differences of successive R-R intervals (rMSSD) (43 vs. 30 ms, p = 0.005) after adjusting for confounders. In addition, the ratio low/high frequency (LF/HF) increased between the 2nd and 3rd tertile (2.3 vs. 3.0, p = 0.04). Among adults, the standard deviation of R-R intervals (SDNN) tended to decrease between the 1st and 2nd tertile (84 vs. 75 ms, p = 0.069) after adjusting for confounders. Furthermore, diastolic BP tended to increase between the 2nd and 3rd tertile (86 vs. 91 mm Hg, p = 0.09). No significant difference was observed in resting HR or pulse pressure (PP) Conclusions Mercury was associated with decreased HRV among French Polynesian teenagers while no significant association was observed with resting HR, BP, or PP among teenagers or adults
机译：背景饮食中富含海鲜的人群高度暴露于汞等污染物中，这可能会影响心血管危险因素。目的评估汞与血压（BP），静息心率（HR）和HR变异性（HRV）之间的关系。法属波利尼西亚人的方法收集了180名成人（≥18岁）和101名青少年（12-17岁）的数据。使用两个小时的动态心电图（Holter）测量HRV，并使用标准化方案测量BP。使用方差分析（ANOVA）和协方差分析（ANCOVA）研究了汞与HRV和BP参数之间的关联。结果在青少年中，第二个和第三个三分位数之间的高频（HF）有所降低（380 vs. 204 ms2，p = 0.03），并且在调整了混杂因素之后，连续RR间隔（rMSSD）的均方差的平方根（43 vs. 30 ms，p = 0.005）观察到了相似的模式。此外，第二/第三分位数之间的低频/高频比率（LF / HF）有所增加（2.3对3.0，p = 0.04）。在成年人中，在调整了混杂因素之后，R-R间隔（SDNN）的标准偏差在第一和第二个三分位数之间趋于减小（84 vs. 75 ms，p = 0.069）。此外，舒张压BP倾向于在第二和第三三分位数之间增加（86 vs. 91 mm Hg，p = 0.09）。结论静息心率或脉搏压（PP）差异无统计学意义结论水银与法属波利尼西亚青少年心率变异性降低相关，而青少年或成年人静息心率，血压或PP无明显关联

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