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A novel cardiac output response to stress test developed to improve diagnosis and monitoring of heart failure in primary care

机译:开发了一种对压力测试的新型心输出量反应,以改善初级保健中心力衰竭的诊断和监测

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Aims Primary care physicians lack access to an objective cardiac function test. This study for the first time describes a novel cardiac output response to stress (CORS) test developed to improve diagnosis and monitoring of heart failure in primary care and investigates its reproducibility. Methods and results Prospective observational study recruited 32 consecutive primary care patients (age, 63?±?9?years; female, n ?=?18). Cardiac output was measured continuously using the bioreactance method in supine and standing positions and during two 3?min stages of a step‐exercise protocol (10 and 15 steps per minute) using a 15?cm height bench. The CORS test was performed on two occasions, i.e. Test 1 and Test 2. There was no significant difference between repeated measures of cardiac output and stroke volume at supine standing and Stage 1 and Stage 2 step exercises (all P 0.3). There was a significant positive relationship between Test 1 and Test 2 cardiac outputs ( r ?=?0.92, P ?=?0.01 with coefficient of variation of 7.1%). The mean difference in cardiac output (with upper and lower limits of agreement) between Test 1 and Test 2 was 0.1 (?1.9 to 2.1)?L/min, combining supine, standing, and step‐exercise data. Conclusions The CORS, as a novel test for objective evaluation of cardiac function, demonstrates acceptable reproducibility and can potentially be implemented in primary care.
机译:目的初级保健医师无法进行客观的心脏功能检查。这项研究首次描述了一种新的针对压力的心输出量反应(CORS)测试,旨在改善初级保健中心力衰竭的诊断和监测,并研究其可重复性。方法和结果前瞻性观察性研究招募了32名连续的初级保健患者(年龄63岁±9岁;女性n岁= 18岁)。使用生物反应法在仰卧位和站立位以及在15厘米高的工作台上的两个3分钟的逐步锻炼方案(每分钟10和15个步骤)阶段连续测量心输出量。 CORS测试是在两种情况下进行的,即测试1和测试2。在仰卧站立和第1阶段和第2阶段逐步锻炼中重复测量心输出量和中风量之间没有显着差异(所有P> 0.3)。试验1和试验2的心输出量之间存在显着的正相关(r = 0.92,P = 0.01,变异系数为7.1%)。测试1和测试2的平均心输出量(具有协议的上下限)的平均差为0.1(?1.9到2.1)?L / min,结合仰卧,站立和逐步锻炼数据。结论CORS是一种用于客观评估心脏功能的新颖测试方法,具有可重复性,可以在基层医疗中实施。

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