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首页> 外文期刊>African Journal of Microbiology Research >Aetiology, antimicrobial susceptibility and predictors of urinary tract infection among febrile under-fives at Muhimbili National Hospital, Dar es Salaam-Tanzania
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Aetiology, antimicrobial susceptibility and predictors of urinary tract infection among febrile under-fives at Muhimbili National Hospital, Dar es Salaam-Tanzania

机译：坦桑尼亚达累斯萨拉姆Muhimbili国家医院发热性五岁以下未成年人五岁以下人群的病因，抗菌素敏感性和尿路感染的预测因子

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Urinary tract infection (UTI) is a common cause of fever in children and contributes to morbidity and mortality. This study aimed at determining prevalence, aetiology and antimicrobial susceptibility pattern of the isolates at Muhimbili National Hospital (MNH), Dar es Salaam- Tanzania. Demographic data were collected using a pretested questionnaire. 382 febrile children below five years admitted in the general paediatric wards were recruited. Urine specimens were obtained for urinalysis, culture and antimicrobial sensitivity testing. UTI was detected in 16.8% (64/382). Children who presented prolonged duration of fever (7 days or longer) were more likely to have UTI (p< 0.01). Duration of fever, positive leukocyte and nitrite tests were independent predictors of UTI. Isolated bacteria included?Escherichia coli?(39.1%),?Klebsiella?spp (31.2%),?Staphylococcus epidermidis?(6.2%),?Staphylococcus aureus?(4.7%) and?Pseudomonas aeruginosa(4.7%). We observed high resistance of the isolated uropathogens to ampicillin (79.9%), co-trimoxazole (89%) and clavulanate-amoxillin (70.3%). Amikacin had the least resistance (12.5%) from the isolated pathogens.
机译：尿路感染（UTI）是儿童发烧的常见原因，并且会增加发病率和死亡率。这项研究旨在确定坦桑尼亚达累斯萨拉姆Muhimbili国家医院（MNH）分离株的患病率，病原学和抗菌药敏感性模式。使用预先测试的问卷收集人口统计数据。招募了382名在普通儿科病房内收治的5岁以下发热儿童。获得尿液样本用于尿液分析，培养和抗菌敏感性测试。检出的UTI率为16.8％（64/382）。发烧时间较长（7天或更长时间）的儿童更可能患有尿路感染（p <0.01）。发热持续时间，白细胞和亚硝酸盐检测阳性是UTI的独立预测因子。分离出的细菌包括大肠杆菌（39.1％），克雷伯菌（31.2％），表皮葡萄球菌（6.2％），金黄色葡萄球菌（4.7％）和铜绿假单胞菌（4.7％）。我们观察到分离的尿路致病菌对氨苄西林（79.9％），复方新诺明（89％）和克拉维酸-氨西林（70.3％）的耐药性较高。阿米卡星对分离出的病原体的抵抗力最低（12.5％）。

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