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首页> 外文期刊>African Journal of Pharmacy and Pharmacology >Analysis of the correlation between morning sickness and rhesus status in pregnant women in Nigeria
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Analysis of the correlation between morning sickness and rhesus status in pregnant women in Nigeria

机译:尼日利亚孕妇晨吐与恒河猴状况的相关性分析

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Erythroblastosis fetalis is a haemolytic disease of the rhesus negative [Rh-?]? mother after the first gestation of a[ Rh+] neonate. Morning sickness (MS) describes a series of neuro-endocrine disturbances characterized by nausea, hyperemesis gravidarum, nutritional selectivity, general debility, confusion and sometimes coma, especially in early pregnancy. It may be mild, moderate or severe and if managed unprofessionally may lead to teratogenicity, recurrent abortion or persistent neonatal death. The influence of the Rhesus negative factor on the intensity of MS was studied in 100 [Rh-] mothers. Another sample of 100 mothers served as control. The studied women were drawn from different social and tribal backgrounds. The study was conducted via questionnaires, personal interviews and medical history of the subjects obtained with their oral consent and that of their doctors. Data analysis showed that about 70% of the [Rh-] negative women belonged to blood group O, 22% to A, 40% to B, and 2% to AB.? There was no significant difference (p > 0.05) in the intensity and duration of MS between the test and control groups. Using the number of MS cases as an index, there were 90% cases of MS in [Rh-] test and 88% cases in [Rh+] control groups respectively. The number of live births for each group was similar with 262 and 194 for [Rh+] mothers and [Rh-] ones submitted to IgG Anti D (Rhagam) therapy. This study has established higher incidence of [Rh-] factor in blood group O in the sample population. It did not establish any relationship between the intensity of MS and Rhesus negative pregnant women. We, therefore, conclude that MS is independent of Rhesus status in pregnant women.
机译:胎儿成纤维细胞病是恒河猴阴性的溶血性疾病[Rh-α]? a Rh +新生儿第一次妊娠后的母亲。晨吐(MS)描述了一系列神经内分泌失调,其特征为恶心,妊娠呕吐,营养选择性,全身虚弱,神志不清,有时甚至昏迷,尤其是在怀孕初期。它可能是轻度,中度或重度的,如果不专业地处理可能会导致致畸性,反复流产或持续性新生儿死亡。在100名[Rh-]母亲中研究了恒河猴阴性因子对MS强度的影响。另取100名母亲作为样本。被研究的女性来自不同的社会和部落背景。该研究是通过问卷,个人访谈和经口头同意的受试者及其医生的病史进行的。数据分析显示,[Rh-]阴性女性中约有70%属于O型血型,A型为22%,B型为40%,AB型为2%。测试组和对照组之间的MS强度和持续时间无显着差异(p> 0.05)。以MS病例数为指标,在[Rh-]试验中分别有90%的MS病例和[Rh +]对照组中的88%病例。每组的活产数与[Rh +]母亲和[Rh-]母亲接受IgG Anti D(Rhagam)治疗的262和194个相似。这项研究确定了样本人群中O型血中[Rh-]因子的发生率较高。它并没有建立MS强度和恒河猴阴性孕妇之间的任何关系。因此,我们得出结论,孕妇的MS与恒河猴状态无关。

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