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首页> 外文期刊>African Journal of Microbiology Research >The anti-bacterial effects of Zataria multiflora extract on common pathogenic Gram positive cocci, pathogenic Gram negative bacilli and non -pathogenic bacteria
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The anti-bacterial effects of Zataria multiflora extract on common pathogenic Gram positive cocci, pathogenic Gram negative bacilli and non -pathogenic bacteria

机译：百日草提取物对常见致病性革兰氏阳性球菌，致病性革兰氏阴性菌和非致病菌的抗菌作用

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摘要

Due to increased bacterial resistance to common antibiotics, tendency towards using herbal extracts like?Zataria multiflora?from Lamiaceae family is increasing. In this study, antibacterial effects of?Z. multiflora?on several common pathogenic and non pathogenic bacteria were evaluated. Several clinical Gram positive cocci and Gram negative bacilli isolated from patients and healthy humans were identified with standard methods. The extract of?Z. multiflora?was prepared from dried leaves with maceration method. The antibacterial activity of?Zataria?extract with initial concentration of 200 μg/ml was determined by micro dilution method. Results obtained showed that the minimum inhibitory concentration varied from 2 to 32 μg/ml for all Gram positive cocci and Gram negative rods while it was 512 μg/ml for?Pseudomonas aeroginosa?and?Shewanella putrifaciance.?The minimum bactericidal concentration varied from 4 to 512 μg/ml for examined bacteria. In conclusion, it seems that?Zataria?extract could inhibit the growth of some clinical Gram positive and Gram negative bacteria. However, the inhibitory effects ofZataria?extract for?Pseudomonas aeroginsa?and?Shewanella putrifacians?are lower than its inhibitory effects for other Gram negative bacilli in the examined extract concentrations. We noticed that the bactericidal effect of?Zataria?extract was less?than its bacteriostatic effect.
机译：由于细菌对常见抗生素的抵抗力增强，因此使用草药提取物（如唇形科的百日草）的趋势正在增加。在这项研究中，抗菌作用为？Z。对几种常见的致病性和非致病性细菌进行了多菌种评估。用标准方法鉴定了从患者和健康人中分离出的几种临床革兰氏阳性球菌和革兰氏阴性菌。 Z的提取物。用浸软法从干叶中制备何首乌。用微量稀释法测定初始浓度为200μg/ ml的Z属提取物的抗菌活性。结果表明，所有革兰氏阳性球菌和革兰氏阴性菌的最低抑菌浓度在2至32μg/ ml之间，而“铜绿假单胞菌”和“希瓦氏菌”的最低抑菌浓度为512μg/ ml。最低杀菌浓度在4范围内变化到512μg/ ml的细菌。综上所述，似乎可以用百日草提取物抑制某些临床革兰氏阳性和阴性细菌的生长。然而，在所检测的提取物浓度下，百日草提取物对绿脓杆菌和恶臭希瓦氏菌的抑制作用低于其对其他革兰氏阴性杆菌的抑制作用。我们注意到，百日草提取物的杀菌作用小于其抑菌作用。

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