首页> 外文期刊>European Journal of Histochemistry >Ultrastructure of telocytes, a new type of interstitial cells in the myocardium of the Chinese giant salamander (Andrias davidianus)
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Ultrastructure of telocytes, a new type of interstitial cells in the myocardium of the Chinese giant salamander (Andrias davidianus)

机译:巨型中国sal(Andrias davidianus)心肌中一种新型的间质细胞,tel细胞的超微结构

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Telocytes (TCs) are new interstitial cells, and they are involved in tissue regeneration, particularly in heart. Therefore, TCs are suggested to be a promising cell in regenerative medicine. However, the information of location structural characteristics and functions of TCs is still limited. In this study, cardiac TCs of the Chinese giant salamanders (Andrias davidianus) were identified by transmission electron microscopy. TCs were located in the interstitium between cardiomyocytes (CM). TCs possessed distinctive ultrastructural characteristics, including one to two very long and thin moniliform telopodes (Tps), emerging points from the cell body, caveolae, dichotomous branchings, labyrinthic systems, neighbouring exosomes and homo-cellular contacts between Tps. TCs/Tps were frequently observed in close proximity to cardiomyocytes. Moreover, Tps established hetero-cellular contacts with cardiomyocytes. Our results confirm the presence of TCs in the myocardium of the A. davidianus. This will help us to better understand roles of TCs in amphibian hearts.
机译:telocytes(TCs)是新的间质细胞,它们参与组织再生,特别是心脏再生。因此,TC被认为是再生医学中有希望的细胞。但是,TC的位置结构特征和功能信息仍然有限。在这项研究中,通过透射电子显微镜鉴定了中国巨型sal(Andrias davidianus)的心脏TC。 TC位于心肌细胞(CM)之间的间质中。 TC具有独特的超微结构特征,包括一到两个非常长且很细的念珠状telopodes(Tps),来自细胞体的新出现的点,海绵体,二分枝,迷宫系统,邻近的囊泡以及Tps之间的同细胞接触。经常在靠近心肌细胞的地方观察到TCs / Tps。而且,Tps建立了与心肌细胞的异细胞接触。我们的结果证实了在大卫曲霉的心肌中存在TC。这将帮助我们更好地了解TC在两栖动物心脏中的作用。

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