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首页> 外文期刊>European Journal of Dentistry >Effects of Low-Intensity Pulsed Ultrasound on Dental Implant Osseointegration: A Preliminary Report
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Effects of Low-Intensity Pulsed Ultrasound on Dental Implant Osseointegration: A Preliminary Report

机译：低强度脉冲超声对牙种植体骨整合的影响：初步报告

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ObjectivesThe aim of this pilot study was to evaluate the effects of low intensity pulsed ultrasound (LIPU) on dental implant osseointegration in a rabbit model using mechanical-histomorphometric methods and resonance-frequency analysis (RFA).MethodsTwelve skeletally mature, male New Zealand rabbits (3.4 kg±0.5) were included in the study. A total number of 24 implants were placed bilaterally into the tibiae of the subjects. The right tibia of each rabbit received LIPU application (20 min/day) while the left side received sham treatment. The study was carried on for six weeks and the rabbits were sacrificed in 7 days intervals (two rabbits for each week). The rabbits were categorized in the early or late osseointegration period according to their sacrification date. Comparisons between the groups were made using statistical analysis of histomorphometric analysis, resonance frequency analysis and mechanical tests.ResultsThe histomorphometry parameters showed that the bone area and the bone volume values have significantly increased in the early osseointegration period and the bone-implant contact values have significantly increased in the late osseointegration period in the LIPU treated subjects when compared to the control group. RFA scores had mild increase in the LIPU group. However the difference was not statistically significant. Mechanical test results suggest an increased mechanical stability in the LIPU group as well.ConclusionsResults of this pilot study indicate that low intensity pulsed ultrasound may have positive effects on osseointegration and stability of dental implants.
机译：目的本研究的目的是使用机械组织形态计量学方法和共振频率分析（RFA）评估低强度脉冲超声（LIPU）对兔模型中牙种植体骨整合的影响。方法12具骨骼骨骼成熟的雄性新西兰兔（ 3.4 kg±0.5）包括在研究中。将总共​​24个植入物双侧置于受试者的胫骨中。每只兔子的右胫骨接受LIPU施用（20分钟/天），而左侧接受假手术治疗。该研究进行了六周，并且每隔7天处死兔子（每周两次）。根据兔的牺牲日期将其在骨整合早期或晚期进行分类。结果通过组织形态计量学分析，共振频率分析和力学性能测试进行了比较。结果组织形态计量学参数表明，在骨整合初期，骨面积和骨体积值显着增加，而骨-植入物的接触值显着增加。与对照组相比，LIPU治疗的受试者在骨整合后期的骨密度增加。 LIPU组的RFA分数有轻度增加。但是，差异在统计上并不显着。力学测试结果表明，LIPU组的机械稳定性也有所提高。结论该初步研究结果表明，低强度脉冲超声可能对牙科植入物的骨整合和稳定性产生积极影响。

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