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The contribution of twin studies to the understanding of the aetiology of asthma and atopic diseases

机译：双生子研究对理解哮喘和特应性疾病的病因学的贡献

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The prevalence of asthma and other atopic diseases has increased markedly during the past decades and the reasons for this are not fully understood. Asthma is still increasing in many parts of the world, notably in developing countries, and this emphasizes the importance of continuing research aimed at studying the aetiological factors of the disease and the causes of its increase in prevalence. Twin studies enable investigations into the genetic and environmental causes of individual variation in multifactorial diseases such as asthma. Thorough insight into these causes is important as this will ultimately guide the development of preventive strategies and targeted therapies. This review explores the contribution of twin studies to the understanding of the aetiology of asthma and atopic diseases.
机译：在过去的几十年中，哮喘和其他特应性疾病的患病率显着增加，其原因尚不完全清楚。哮喘在世界许多地区仍在增加，特别是在发展中国家，这强调了继续进行研究以研究该病的病因和流行率增加原因的重要性。双胞胎研究使人们能够调查哮喘等多因素疾病个体变异的遗传和环境原因。深入了解这些原因很重要，因为这将最终指导预防策略和靶向疗法的发展。这篇综述探索了双生子研究对理解哮喘和特应性疾病的病因学的贡献。

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