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首页> 外文期刊>European Journal of Medicinal Plants >Evaluation of Anti-bacterial Activity of Silybum marianum against Pathogenic and Resistant Bacteria
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Evaluation of Anti-bacterial Activity of Silybum marianum against Pathogenic and Resistant Bacteria

机译：水飞蓟素对致病性和抗性细菌的抗菌活性评估

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Aims: Our arsenal of antibiotics is running low due to overuse and misuse of these lifesaving drugs. Much research is needed on medicinal plants to look for drugs to tackle this issue Methodology: so antibacterial activity of organic extracts of Silybum marianum was evaluated against Methicillin-resistant Staphylococcus aureus (MRSA), resistant E. coli , ATCC 12361, ATCC 12466 and ATCC 13581. Inhibition of bacterial growth was determined using agar well diffusion methods. Results: Among all assayed organic extracts only Dimethylformamide presented highest activities against all tested strains except resistant E. coli. Dimethylformamide and Methanol showed better activity than cephradine against ACTT 13581. The Dichloromethane extract showed no antibacterial activity against any strains. Methanol and Isopropyl Alcohol showed moderate activities against all tested strains. S. marianum would be an interesting topic for further study and possibly for an alternative treatment for resistant and pathogenic bacterial infections.
机译：目的：由于过度使用和滥用这些救生药物，我们的抗生素库中的抗生素正在减少。需要对药用植物进行大量研究以寻找药物来解决这个问题。方法：因此，对水飞蓟有机提取物的抗菌活性进行了评估，以评估耐甲氧西林的金黄色葡萄球菌（MRSA），抗性的大肠杆菌，ATCC 12361，ATCC 12466和ATCC 13581.使用琼脂井扩散方法确定细菌生长的抑制作用。结果：在所有测定的有机提取物中，只有二甲基甲酰胺对除抗性大肠埃希菌外的所有测试菌株表现出最高的活性。二甲基甲酰胺和甲醇显示出比头孢拉定对ACTT 13581更好的活性。二氯甲烷提取物对任何菌株均无抗菌活性。甲醇和异丙醇对所有测试菌株均显示中等活性。 S. marianum将是一个有趣的话题，需要进一步研究，并可能成为耐药和致病性细菌感染的替代治疗方法。

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