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首页> 外文期刊>European Journal of Medicinal Plants >Comparative Anti-oxidant Activity of Aqueous and Organic Extracts from Kenyan Ruellia linearibracteolata and Ruellia bignoniiflora
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Comparative Anti-oxidant Activity of Aqueous and Organic Extracts from Kenyan Ruellia linearibracteolata and Ruellia bignoniiflora

机译：肯尼亚线型Ruellia linearibracteolata和大果Ruellia bignoniiflora的水和有机提取物的比较抗氧化活性

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Medicinal plants play a significant role in treatment and prevention of many diseases in humans worldwide. Ruellia species belong to the family Acanthaceae and have been used widely for medicinal purposes. The objective of this study was to evaluate the comparative In vitro anti-oxidant activity of two Kenyan Ruellia species viz. Ruellia lineari-bracteolata (RLB) and Ruellia bignoniiflora (RBK). The plant materials were extracted with aqueous, ethyl acetate and methanol. The extracts were subjected to phytochemical screening according to standard procedures and anti-oxidant activity determined using 2, 2-Diphenyl-1-picrylhydrazyl (DPPH) assay. Comparative anti-oxidant activity for methanolic, ethyl acetate and aqueous extracts of RLB and RBK exhibited IC50 values of (2.7, 29.3, 7.2 and 24.4, 237.2, 66.4 μg/ml) respectively. Among the three extracts, methanolic extract showed better activity (2.7 μg/ml) comparable to ascorbic standard (2.1 μg/ml). Between the two Ruellia species, RLB showed a significant difference (p<0.05) in anti-oxidant activity as compared to RBK extracts. Phytochemical screening showed the presence of terpenoids, saponins, flavonoids, tannins and glycosides. Flavonoids and tannins are the main phytoconstituents responsible for anti-oxidant activity. In conclusion, the potent anti-oxidant activity of these plants makes them useful in development of medicinal drugs for treatment and prevention of degenerative diseases.
机译：药用植物在全世界人类的许多疾病的治疗和预防中起着重要作用。芸苔属植物属于棘皮科，已被广泛用于医药目的。这项研究的目的是评估两种肯尼亚Ruellia种的比较体外抗氧化活性。小叶芸苔（RLB）和大果芸苔（RBK）。用水性，乙酸乙酯和甲醇萃取植物材料。根据标准程序对提取物进行植物化学筛选，并使用2，2-二苯基-1-吡啶并肼基（DPPH）测定法测定抗氧化活性。 RLB和RBK的甲醇，乙酸乙酯和水提取物的比较抗氧化活性分别显示IC 50 值（2.7、29.3、7.2和24.4、237.2、66.4μg/ ml）。在三种提取物中，甲醇提取物显示出比抗坏血标准品（2.1μg/ ml）更好的活性（2.7μg/ ml）。在两个Ruellia物种之间，与RBK提取物相比，RLB的抗氧化活性有显着差异（p <0.05）。植物化学筛选显示存在萜类，皂苷，类黄酮，单宁和糖苷。类黄酮和单宁酸是负责抗氧化活性的主要植物成分。总之，这些植物强大的抗氧化活性使它们可用于开发治疗和预防退行性疾病的药物。

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