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首页> 外文期刊>European Journal of Histochemistry >An investigation of an autonomic innervation of the vertebral artery using monoamine histofluorescence
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An investigation of an autonomic innervation of the vertebral artery using monoamine histofluorescence

机译:单胺组织荧光法研究椎动脉的自主神经

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摘要

Blood flow to the hindbrain, via the paired vertebral arteries, must be uncompromised for adequate neurological functioning of its vital centres. Therefore, it would seem unlikely that the intracranial vertebral artery would need to vasoconstrict, thus reducing its blood flow. In order to investigate the existence and location of a noradrenaline-mediated constrictor mechanism in the wall of the intracranial vertebral artery, transverse sections of ten baboon and ten monkey vessels were stained with sucrose-potassium phosphate-glyoxylic acid (counterstained with malachite-green). This method allows the visualisation of catecholaminergic nerves when the sections are exposed to ultraviolet light. In this study of primate vascular tissue, however, of the monkey or baboon vertebral artery sections showed the presence of noradrenergic nerves in the tunica media tunica adventitia junction or penetrating the tunica media of the arteries. These findings indicate that the intracranial vertebral artery does not have a neurogenic vasomotor function in primates.
机译:通过成对的椎动脉流到后脑的血液必须毫不妥协,以确保其重要中枢的神经功能正常。因此,似乎不太可能需要颅内椎动脉进行血管收缩,从而减少其血流量。为了研究去甲肾上腺素介导的收缩器机制在颅内椎动脉壁中的存在和位置,用蔗糖-磷酸钾-乙醛酸(用孔雀石绿)染色了十只狒狒和十只猴子血管的横切面。 。当切片暴露于紫外线下时,该方法可以使儿茶酚胺能神经可视化。然而,在这项关于灵长类动物血管组织的研究中,猴子或狒狒椎动脉切片显示中膜中膜外膜结合处或穿透动脉中膜中存在去甲肾上腺素能神经。这些发现表明,颅内椎动脉在灵长类动物中不具有神经源性血管舒缩功能。

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