...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>European Journal of Histochemistry >Influence of surgical and chemical orchidectomy on weight and distribution of AChE-nerve fibres in thymuses of adult rats
【24h】

Influence of surgical and chemical orchidectomy on weight and distribution of AChE-nerve fibres in thymuses of adult rats

机译：手术和化学性兰花切除术对成年大鼠胸腺AChE神经纤维重量和分布的影响

获取原文
   

获取外文期刊封面封底 >>

       
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

The thymus is a crossroad between the immune and neuroendocrine systems. As such, it is innervated by acetylcholinesterase (AChE)-positive fibres of the vagus, the recurrent laryngeal and the phrenic nerves. It is well know, that the innervations density of the thymus increases with age. In our study, adult rats were orchidectomized (surgically and chemically by the application of a luteinizing hormone-releasing hormone). The density of AChE-positive nerve fibres in thymuses, as well as the weight of thymuses was examined. The authors found that both surgical and chemical orchidectomy result in macroscopic and microscopic regeneration of the atrophied thymuses. In regenerated rat’s thymuses after orchidectomy the density of AChE-positive nerve fibres was markedly higher in comparison with the control animals. The distribution, as well as the density of AChE-positive nerve fibres in regenerated thymuses after orchidectomy evokes the images of its innervations like in young animals before age-related involution. The authors also found a markedly higher weight of thymuses of orchidectomized rats in comparison with the control groups. In recent study the authors proved that after 8 weeks surgical orchidectomy leads to the regeneration of thymic AChE-positive innervation and chemical orchidectomy by administration of luteinizing hormone-releasing hormone after 4 weeks of adult rats.
机译：胸腺是免疫系统和神经内分泌系统之间的十字路口。因此，它由迷走神经，喉返神经和en神经的乙酰胆碱酯酶（AChE）阳性纤维支配。众所周知，胸腺的神经支配密度随年龄增长而增加。在我们的研究中，成年大鼠被睾丸切除术（通过使用促黄体激素释放激素进行手术和化学方法）。检查胸腺中AChE阳性神经纤维的密度以及胸腺的重量。作者发现，手术和化学兰花切除术均可导致萎缩性胸腺的宏观和微观再生。与对照组相比，兰花切除后的再生大鼠胸腺中AChE阳性神经纤维的密度明显更高。兰花切除术后再生胸腺中AChE阳性神经纤维的分布及其密度唤起了其神经支配的图像，就像在年龄相关的退化之前的幼小动物一样。作者还发现，与对照组相比，经睾丸切除的大鼠胸腺重量明显更高。在最近的研究中，作者证明了成年大鼠4周后给予黄体生成激素释放激素后，经过8周的手术性兰花切除术可导致胸腺AChE阳性神经支配和化学性兰花切除术的再生。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号