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首页> 外文期刊>European Journal of General Medicine >Metabolic Syndrome in Younger Patients with Acute Coronary Syndrome
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Metabolic Syndrome in Younger Patients with Acute Coronary Syndrome

机译：年轻的急性冠脉综合征患者的代谢综合征

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摘要

Metabolic Syndrome (MeS) has reached epidemic proportions among younger individuals. We sought to determine the prevalence of MeS and its influence on the risk of Acute Coronary Syndrome (ACS) in a younger patient population (≤50 years old). Consecutive patients aged < 50 years hospitalized with the first episode of ACS were categorized whether or not they meet the modified NCEP-ATP III criteria for MeS.1 Diabetic patients were excluded. The control group was comprised of subjects with a de novo diagnosis of CAD but without MeS or DM. The prevalence of MeS in the initial sample of 212 patients with ACS was 26% (N=55). Of the 75 subjects included in the final analysis, 55 patients had MeS (C1) and 20 did not (C2). Mean age, sex, LDL, and Framingham risk scores were not significantly different. Patients with MeS were significantly more likely to present with STEMI (OR 12.67, 95% CI 1.98-78.40, P=0.004), and have lower ejection fractions (45±12% vs. 58±3%, p=0.0001). Among patients younger than 50 years presenting with the first episode of ACS, the prevalence of MeS was high even in the absence of traditional cardiovascular risk factors. Increased incidence of STEMI and reduced EFs were more commonly seen among individuals with MeS.
机译：代谢综合症（MeS）已在年轻人中达到流行病的程度。我们试图确定年轻人群（≤50岁）中MeS的患病率及其对急性冠脉综合征（ACS）风险的影响。对首次入院ACS的50岁以下连续患者进行分类，以确认他们是否符合MeS的改良NCEP-ATP III标准。1排除了糖尿病患者。对照组由具有CAD从头诊断但无MeS或DM的受试者组成。 212例ACS患者的初始样本中MeS的患病率为26％（N = 55）。在最终分析中包括的75名受试者中，有55名患有MeS（C1），而没有20名（C2）。平均年龄，性别，LDL和Framingham风险评分没有显着差异。 MeS患者出现STEMI的可能性更高（OR 12.67，95％CI 1.98-78.40，P = 0.004），射血分数较低（45±12％对58±3％，p = 0.0001）。在首发ACS的50岁以下患者中，即使没有传统的心血管危险因素，MeS的患病率仍很高。在患有MeS的患者中，更常见的是STEMI发生率增加和EF降低。

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