Discrete foci containing RNAse A are found in nucleoli of HeLa cells after aging in culture

M. Costanzo; B. Cisterna; O. O. Zharskaya; O. V. Zatsepina; M. Biggiogera

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Discrete foci containing RNAse A are found in nucleoli of HeLa cells after aging in culture

机译：培养中老化后在HeLa细胞的核仁中发现了含有RNA酶A的离散病灶

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We have studied by means of ultrastructural immunocytochemistry the localization of RNase A in nuclei of HeLa cells in control conditions and following cell ageing in culture. We have found that roundish, electron dense foci, which contain a significant amount of RNAse A, can be detected within nucleoli of aged cells. These bodies also contain RNA and lack ribosomal S3 proteins, and may represent either simple storage sites or areas where RNA degradation takes place.

机译：我们已经通过超微结构免疫细胞化学研究了在控制条件下以及培养物中细胞衰老后RNase A在HeLa细胞核中的定位。我们发现，在衰老细胞的核仁中可以检测到圆形的，电子密集的病灶，其中包含大量的RNA酶A。这些小体还包含RNA，缺乏核糖体S3蛋白，可能代表简单的存储位点或发生RNA降解的区域。

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《European Journal of Histochemistry》 |2011年第2期|共页
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M. Costanzo; B. Cisterna; O. O. Zharskaya; O. V. Zatsepina; M. Biggiogera;
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1. Discrete foci containing RNase A are found in nucleoli of HeLa cells aged in culture [J] . M. Costanzo, B. Cisterna, O.O. Zharskaya, European Journal of Histochemistry . 2011,第2期

机译：在培养的HeLa细胞核仁中发现含有RNase A的离散病灶
2. RNase A treatment and reconstitution with DNA damage response RNA in living cells as a tool to study the role of non-coding RNA in the formation of DNA damage response foci [J] . Michelini Flavia, Rossiello Francesca, di Fagagna Fabrizio dAdda, Nature protocols erecipes for researchers . 2019,第5期

机译：RNase一种用DNA损伤反应RNA在活细胞中的治疗和重构作为研究非编码RNA在DNA损伤反应焦点形成中的作用的工具
3. Ascorbic acid and dehydroascorbic acid in HeLa cells: their effect on the collagen-peptidase activity of glucose-deficient cultures [J] . W A Boggust, H McGauley British Journal of Cancer . 1978,第1期

机译：HeLa细胞中的抗坏血酸和脱氢抗坏血酸：它们对葡萄糖缺乏培养物的胶原肽酶活性的影响
4. EVOLUTION OF A COMPETITIVENESS INITIATIVE FROM DISCRETE PROGRAM TO A CONTINUOUS IMPROVEMENT CULTURE THE ANCHORAGE WATER AND WASTEWATER UTILITY'S EXCELLENCE ADVENTURE [C] . Jack Warburton, Brian Crewdson Water Environment Federation annual technical exhibition & conference;WEFTEC 2002 . 2002

机译：从离散计划到持续改进文化的竞争力计划的演变锚固水和废水利用的卓越冒险
5. Studies of RNase P from HeLa cells [D] . Gold, Heidi Abbe. 1988

机译：来自HeLa细胞的RNase p的研究
6. Discrete foci containing RNase A are found in nucleoli of HeLa cells aged in culture [O] . M. Costanzo, B. Cisterna, O.O. Zharskaya, 2011

机译：在培养的HeLa细胞核仁中发现含有RNase A的离散病灶
7. Discrete foci containing RNase A are found in nucleoli of HeLa cells aged in culture [O] . Costanzo, M., Cisterna, B., Zharskaya, O.O., 2011

机译：在培养的HeLa细胞核仁中发现含有RNase A的离散病灶

Discrete foci containing RNAse A are found in nucleoli of HeLa cells after aging in culture

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