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Internet-based prevention of posttraumatic stress symptoms in injured trauma patients: design of a randomized controlled trial

机译:基于Internet的预防受伤患者创伤后应激症状的方法:一项随机对照试验的设计

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Background: Injured trauma victims are at risk of developing Posttraumatic Stress Disorder (PTSD) and other post-trauma psychopathology. So far, interventions using cognitive behavioral techniques (CBT) have proven most efficacious in treating early PTSD in highly symptomatic individuals. No early intervention for the prevention of PTSD for all victims has yet proven effective. In the acute psychosocial care for trauma victims, there is a clear need for easily applicable, accessible, cost-efficient early interventions. Objective: To describe the design of a randomized controlled trial (RCT) evaluating the effectiveness of a brief Internet-based early intervention that incorporates CBT techniques with the aim of reducing acute psychological distress and preventing long-term PTSD symptoms in injured trauma victims. Method: In a two armed RCT, 300 injured trauma victims from two Level-1 trauma centers in Amsterdam, the Netherlands, will be assigned to an intervention or a control group. Inclusion criteria are: being 18 years of age or older, having experienced a traumatic event according to the diagnostic criteria of the DSM-IV and understanding the Dutch language. The intervention group will be given access to the intervention's website (www.traumatips.nl), and are specifically requested to login within the first month postinjury. The primary clinical study outcome is PTSD symptom severity. Secondary outcomes include symptoms of depression and anxiety, quality of life, and social support. In addition, a cost-effectiveness analysis of the intervention will be performed. Data are collected at one week post-injury, prior to first login (baseline), and at 1, 3, 6 and 12 months. Analyses will be on an intention-to-treat basis. Discussion: The results will provide more insight into the effects of preventive interventions in general, and Internet-based early interventions specifically, on acute stress reactions and PTSD, in an injured population, during the acute phase after trauma. We will discuss possible strengths and limitations.
机译:背景:受伤的创伤受害者有发展为创伤后应激障碍(PTSD)和其他创伤后心理病理的风险。迄今为止,事实证明,使用认知行为技术(CBT)进行的干预对于治疗有症状的早期PTSD最有效。尚未证明对所有受害者预防PTSD的早期干预措施都是有效的。在针对创伤受害者的急性社会心理护理中,显然需要易于应用,可及且具有成本效益的早期干预措施。 目的:描述评估随机短期试验(RCT)的设计,该试验评估基于互联网的简短早期干预的有效性,该早期干预结合了CBT技术,旨在减轻急性心理困扰并预防受伤创伤中的长期PTSD症状受害者。方法:在两个武装的RCT中,来自荷兰阿姆斯特丹两个Level-1创伤中心的300名受伤的创伤受害者将被分配到干预组或对照组。入选标准为:年满18岁或以上,根据DSM-IV的诊断标准经历过创伤事件并了解荷兰语。将允许干预组访问干预的网站(www.traumatips.nl),并特别要求在受伤后的第一个月内登录。主要的临床研究结果是PTSD症状的严重程度。次要结果包括抑郁和焦虑症状,生活质量和社会支持。另外,将进行干预的成本效益分析。在受伤后一个星期,第一次登录之前(基线)以及第1、3、6和12个月收集数据。分析将基于意向性处理。讨论:该结果将为一般预防性干预,尤其是基于互联网的早期干预,对创伤后急性阶段受伤人群的急性应激反应和PTSD的影响提供更深入的了解。我们将讨论可能的优势和局限性。

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