...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Eurosurveillance >Clinical implications of Mycobacterium chimaera detection in thermoregulatory devices used for extracorporeal membrane oxygenation (ECMO), Germany, 2015 to 2016
【24h】

Clinical implications of Mycobacterium chimaera detection in thermoregulatory devices used for extracorporeal membrane oxygenation (ECMO), Germany, 2015 to 2016

机译：2015年至2016年在德国用于体外膜氧合（ECMO）的温度调节装置中进行分枝杆菌分枝杆菌检测的临床意义

获取原文
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Mycobacterium chimaera, a non-tuberculous mycobacterium, was recently identified as causative agent of deep-seated infections in patients who had previously undergone open-chest cardiac surgery. Outbreak investigations suggested an aerosol-borne pathogen transmission originating from water contained in heater-cooler units (HCUs) used during cardiac surgery. Similar thermoregulatory devices are used for extracorporeal membrane oxygenation (ECMO) and M. chimaera might also be detectable in ECMO treatment settings. We performed a prospective microbiological study investigating the occurrence of M.?chimaera in water from ECMO systems and in environmental samples, and a retrospective clinical review of possible ECMO-related mycobacterial infections among patients in a pneumological intensive care unit. We detected M.?chimaera in 9 of 18 water samples from 10 different thermoregulatory ECMO devices; no mycobacteria were found in the nine room air samples and other environmental samples. Among 118 ECMO patients, 76 had bronchial specimens analysed for mycobacteria and M.?chimaera was found in three individuals without signs of mycobacterial infection at the time of sampling. We conclude that M.?chimaera can be detected in water samples from ECMO-associated thermoregulatory devices and might potentially pose patients at risk of infection. Further research is warranted to elucidate the clinical significance of M.?chimaera in ECMO treatment settings.
机译：最近已确定，非结核性分枝杆菌chimaera分支杆菌是深部感染的病原，以前曾进行过开胸手术。暴发调查表明，由气溶胶传播的病原体传播源自心脏手术中使用的加热器-冷却器（HCU）中的水。类似的温度调节装置可用于体外膜氧合（ECMO），并且在ECMO治疗环境中也可检测到M. chimaera。我们进行了一项前瞻性微生物研究，调查了ECMO系统和环境样品中水中的M.chimaera的发生，并对肺病重症监护病房患者中可能存在的ECMO相关分枝杆菌感染进行了回顾性临床回顾。我们从10个不同的温度调节ECMO设备的18个水样中，有9个检测到了奇异杆菌。在九个房间的空气样本和其他环境样本中未发现分枝杆菌。在118例ECMO患者中，对76例进行了分枝杆菌分析的支气管标本，在采样时，在3例无分枝杆菌感染迹象的人中发现了支原体。我们得出的结论是，可以从ECMO相关的温度调节设备的水样中检测到奇异分支杆菌，并可能使患者面临感染的危险。有必要进行进一步的研究来阐明奇异分支杆菌在ECMO治疗环境中的临床意义。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号