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首页> 外文期刊>Exchanges: The Warwick Research Journal >Mimicking Bone - Chemical and Physical Challenges
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Mimicking Bone - Chemical and Physical Challenges

机译：模仿骨骼-化学和物理挑战

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It is known that chemical and physical features of bone contribute to its functionality, reactivity and mechanical performance. This article presents a summary of previously published studies conducted by the author with the aim of fabricating a synthetic structure, referred to as a scaffold, which both chemically and physically emulates the intricate structure of bone. Novel work aimed at improving the understanding of the synthesis of a ceramic biomaterial, namely hydroxyapatite, that is chemically similar to bone mineral is discussed. A case study involving the manufacture of porous scaffolds by 3D printing is also presented. In summary, this article highlights a number of on-going challenges that multidisciplinary tissue engineers aim to solve to get one-step closer to mimicking bone, which clinically could improve the quality of life for millions of people worldwide.
机译：众所周知，骨骼的化学和物理特征有助于骨骼的功能，反应性和机械性能。本文提供了作者先前发表的研究的摘要，该研究的目的是制造一种被称为支架的合成结构，该结构在化学和物理上都可以模拟骨骼的复杂结构。讨论了旨在增进对陶瓷生物材料（即羟基磷灰石）合成的理解的新工作，该化学材料与骨矿物质相似。还介绍了一个涉及通过3D打印制造多孔支架的案例研究。总而言之，本文重点介绍了多学科组织工程师旨在解决的一系列挑战，这些挑战旨在使人们更接近于模仿骨骼，这在临床上可以改善全球数百万人的生活质量。

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