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Longevity nutrients resveratrol, wines and grapes

机译：长寿营养白藜芦醇，葡萄酒和葡萄

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摘要

A mild-to-moderate wine drinking has been linked with reduced cardiovascular, cerebrovascular, and peripheral vascular risk as well as reduced risk due to cancer. The reduced risk of cardiovascular disease associated with wine drinking is popularly known as French Paradox. A large number of reports exist in the literature indicating that resveratrol present in wine is primarily responsible for the cardioprotection associated with wine. Recently, resveratrol was shown to extend life span in yeast through the activation of longevity gene SirT1, which is also responsible for the longevity mediated by calorie restriction. This review summarizes the reports available on the functional and molecular biological aspects of resveratrol, wine and grapes in potentiating the longevity genes.
机译：轻度至中度饮酒与降低心血管，脑血管和周围血管的风险以及降低因癌症引起的风险有关。与饮酒有关的心血管疾病的风险降低被普遍称为French Paradox。文献中有大量报告表明葡萄酒中存在的白藜芦醇是与葡萄酒相关的心脏保护作用的主要起因。最近，白藜芦醇被证明可以通过激活长寿基因SirT1来延长酵母的寿命，而长寿基因SirT1也是卡路里限制介导的长寿的原因。这篇综述总结了有关白藜芦醇，葡萄酒和葡萄在增强长寿基因方面的功能和分子生物学方面的报道。

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