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Construction of calibration curve for premature chromosome condensation assay for dose assessment

机译:用于剂量评估的早熟染色体凝结测定的校准曲线的构建

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Cytogenetic dosimetry plays an important role in the triage and medical management of affected people in radiological incidents/accidents. Cytogenetic biodosimetry uses different methods to estimate the absorbed dose in the exposed individuals, and each approach has its advantages and disadvantages. Premature chromosome condensation (PCC) assay presents several advantages that hopefully fulfill the gaps identified in the other cytogenetic methods. To introduce this technique into the panel of other cytogenetic methods, a calibration curve for PCC after γ-irradiation was generated for our laboratory.
机译:细胞遗传学剂量测定在放射事件/事故中对受影响人群的分类和医疗管理中起着重要作用。细胞遗传生物剂量测定法使用不同的方法来估计暴露个体的吸收剂量,每种方法各有其优缺点。早染色体凝集(PCC)测定法具有一些优势,有望填补其他细胞遗传学方法中发现的空白。为了将该技术引入其他细胞遗传学方法中,我们实验室为γ-射线辐照后的PCC绘制了一条校准曲线。

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