Serum levels of PSA, ALP, ICTP, and BSP in prostate cancer patients and the significance of ROC curve in the diagnosis of prostate cancer bone metastases

R.J. Wei; T.Y. Li; X.C. Yang; N. Jia; X.L. Yang; H.B. Song

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Serum levels of PSA, ALP, ICTP, and BSP in prostate cancer patients and the significance of ROC curve in the diagnosis of prostate cancer bone metastases

机译：前列腺癌患者血清PSA，ALP，ICTP和BSP水平以及ROC曲线在前列腺癌骨转移诊断中的意义

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Bone metastasis is a common complication in prostate cancer patients that can cause bone pain and pathological fracture. This study tested serum levels of prostate specific antigen (PSA), alkaline phosphatase (ALP), bone sialoprotein (BSP), collagen type I pyridine crosslinking peptide (ICTP) in prostate cancer patients and the significance of the receiver operator characteristic (ROC) curve in the diagnosis of prostate cancer bone metastases. Eighty-three prostate cancer patients were enrolled including 42 in the bone metastases group and 41 in the non-bone metastases group. Serum levels of BSP, ALP, ICTP, and PSA were highest in the bone metastases group followed by the non-bone metastases group, hyperplasia group, and then the control group (P

机译：骨转移是前列腺癌患者的常见并发症，可引起骨痛和病理性骨折。这项研究测试了前列腺癌患者的前列腺特异性抗原（PSA），碱性磷酸酶（ALP），骨唾液蛋白（BSP），I型胶原吡啶交联肽（ICTP）的血清水平以及接收者操作者特征曲线（ROC）的意义在前列腺癌骨转移的诊断中。八十三例前列腺癌患者入组，其中骨转移组42例，非骨转移组41例。骨转移组的血清BSP，ALP，ICTP和PSA水平最高，其次是非骨转移组，增生组，然后是对照组（P

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《Genetics and Molecular Research》 |2016年第2期|共9页
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R.J. Wei; T.Y. Li; X.C. Yang; N. Jia; X.L. Yang; H.B. Song;
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1. Serum BSP, PSADT, and Spondin-2 levels in prostate cancer and the diagnostic significance of their ROC curves in bone metastasis [J] . B.-P. Zhu, Z.-Q. Guo, L. Lin, European review for medical and pharmacological sciences. . 2017,第1期

机译：血清BSP，Psadt和纯素-2水平在前列腺癌中以及其ROC曲线在骨转移中的诊断意义
2. Prognostic Significance of Time to Prostate-Specific Antigen (PSA) Nadir and Its Relationship to Survival Beyond Time to PSA Nadir for Prostate Cancer Patients With Bone Metastases After Primary Androgen Deprivation Therapy [J] . Teoh Jeremy Yuen Chun, Tsu James Hok Leung, Yuen Steffi Kar Kei, Annals of surgical oncology . 2015,第4期

机译：原发性雄激素剥夺治疗后前列腺癌骨转移患者的前列腺特异性抗原（PSA）最低点时间的预后意义及其与生存时间的关系
3. Serum bone turnover markers (PINP and ICTP) for the early detection of bone metastases in patients with prostate cancer: a longitudinal approach. [J] . Koopmans N, de-Jong IJ, Breeuwsma AJ, The Journal of Urology . 2007,第3aPta1期

机译：用于早期检测前列腺癌患者骨转移的血清骨转换标记物（PINP和ICTP）：纵向方法。
4. Serum levels of sex hormones before and after androgen deprivation therapy in Japanese prostate cancer patients [C] . A. Komiya, K. Ichimatsu, A. Morii, International Congress of Andrology . 2009

机译：日本前列腺癌患者中雄激素剥夺治疗前后的性激素血清水平
5. Diet and prostate cancer: Investigating the relationship between risk of prostate cancer and serum concentrations of individual carotenoids, selenium, and alpha-tocopherol in United States Black and White men. [D] . Vogt, Tara Michelle. 2001

机译：饮食和前列腺癌：研究美国黑人和白人中前列腺癌风险与个体类胡萝卜素，硒和α-生育酚的血清浓度之间的关系。
6. Significance of Serum Testosterone for Prostate-Specific Antigen (PSA) Elevation and Prediction of Prostate Cancer in Patients with PSA Above 10 ng/ml [O] . Jin Mo Koo, Bong Suk Shim 2010

机译：血清睾丸激素对PSA高于10 ng / ml的患者前列腺特异性抗原（PSA）升高和前列腺癌预测的意义
7. Measurement of serum PSA values by DELFIA PSA and its clinical significance on diagnosis and follow-up of prostate cancer patients [O] . 栗山学, 江崎奈々, 山田伸一郎, 1992

机译：DELFIA PSA测定血清PSA值及其对前列腺癌患者诊断和随访的临床意义

Serum levels of PSA, ALP, ICTP, and BSP in prostate cancer patients and the significance of ROC curve in the diagnosis of prostate cancer bone metastases

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