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首页> 外文期刊>Global Journal of Health Science >Effect of Percutaneous Coronary Intervention on Left Ventricular Diastolic Function in Patients With Coronary Artery Disease
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Effect of Percutaneous Coronary Intervention on Left Ventricular Diastolic Function in Patients With Coronary Artery Disease

机译：经皮冠状动脉介入治疗对冠心病患者左​​室舒张功能的影响

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BACKGROUND: There is considerable disagreement over the effects of percutaneous coronary intervention (PCI) on left ventricular diastolic function that has necessitated the investigation of diastolic indices. The present study was conducted to evaluate left ventricular diastolic function and its indices, three months after performing the PCI procedure in patients with coronary artery disease (CAD). METHODS: In a quasi-experimental clinical trial study (before and after), 51 patients with CAD scheduled for elective PCI were investigated provided that their Ejection Fraction (EF) was > 30%. Before and three months after PCI, echocardiography was carried out to evaluate left ventricular diastolic indices including the E/Ea as the most important criteria for diagnosis of diastolic heart failure (DHF). RESULTS: Based on the E/Ea indices and after PCI, the number of patients with DHF decreased significantly: 40 patients (78.4%) before PCI versus 28 patients (54.9%) after PCI (p<0.05). The Mean and Standard error of deceleration time (DT), isovolumic relaxation time (IVRT), early diastolic mitral annulus velocity; Ea (E'), E/Ea and left ventricular ejection function (LVEF) indices underwent significant changes. In addition, MVA dur/PVA dur, PVs/PVd, and E/Ea indices had changed significantly after PCI in both genders. However, no significant difference was reported for the other indices. CONCLUSION: The E/Ea ratio as an important criterion for diagnosis of DHF was improved after PCI. Improvement of several other diastolic indices was observed after the PCI procedure. It can be concluded that PCI can be an effective treatment modality in patients with left ventricular diastolic indices.
机译：背景：关于经皮冠状动脉介入治疗（PCI）对左心室舒张功能的影响存在很大分歧，这需要研究舒张指数。本研究旨在评估冠状动脉疾病（CAD）患者进行PCI手术后三个月的左心室舒张功能及其指标。方法：在一项准实验性临床试验研究中（前后），对51例计划行择期PCI的CAD患者进行了调查，条件是其射血分数（EF）> 30％。 PCI术前和术后三个月，进行了超声心动图检查以评估包括E / Ea在内的左心室舒张指数，作为诊断舒张性心力衰竭（DHF）的最重要标准。结果：基于E / Ea指数和PCI后，DHF患者的数量显着减少：PCI前40例（78.4％），而PCI后28例（54.9％）（p <0.05）。减速时间（DT），等容舒张时间（IVRT），舒张早期二尖瓣环速的平均和标准误差; Ea（E'），E / Ea和左心室射血功能（LVEF）指标发生了显着变化。此外，PCI后，男女的MVA dur / PVA dur，PVs / PVd和E / Ea指数均发生了显着变化。但是，其他指数均无显着差异。结论：PCI后，E / Ea比值成为诊断DHF的重要指标。 PCI术后观察到其他一些舒张指数的改善。可以得出结论，PCI可以成为左心室舒张指数高的患者的有效治疗方式。

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