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Study on Hematologic Changes Associated with Hepatic Alterations Observed in Sheep

机译：绵羊肝功能改变相关血液学变化的研究

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The present study investigates the effect of liver as compared to non-liver diseases on somehematological parameters, including hematocrit, leukocyte count and the leukocyte formula. Macroscopicexaminations of liver were conducted to select 45 slaughtered sheep distributed into three groups (15 samplesfor each group). Group A included sheep with affected livers; group B was made up of sheep with affectedlungs and without hepatic lesions and group C was the control group that included healthy animals.Common lesions to the liver and lungs (hydatid cysts, abscesses and fibrosis) were recorded given the higherprevalence in group A compared to group B (hydatid cysts 15.5% vs 8.8%) and abscesses (15.5% vs 6.6%),respectively. The prevalence of fibrosis was higher in group B (6.6%) compared to group A (2.2%). Certainhematological parameters for the three groups showed a hematocrit that was significantly lower (p<0.01) anda marked decrease (p<0.01) of the absolute value of lymphocytes and the basophils were significant higher(p<0.01) in group A. However, monocytosis, eosinopenia and lymphopenia (p<0.01) were recorded in groupB. A decrease in hematocrit values and lymphocytes and an increase in basophils were significant in liverlesions. Hematocrit and leukocyte formula are important diagnostic parameters in determination of hepaticaffections in sheep.
机译：本研究调查了与非肝脏疾病相比，肝脏对某些血液学参数（包括血细胞比容，白细胞计数和白细胞配方）的影响。进行肝的肉眼检查，以选择45只屠宰的绵羊，将其分成三组（每组15个样品）。 A组包括肝脏受影响的绵羊; B组由患肺且无肝病灶的绵羊组成，C组为健康动物的对照组，由于与A组相比患病率更高，因此记录了肝和肺的常见病灶（包虫囊肿，脓肿和纤维化）。 B组（包虫囊肿分别为15.5％和8.8％）和脓肿（分别为15.5％和6.6％）。与A组（2.2％）相比，B组（6.6％）的纤维化患病率更高。三组的某些血液学参数显示，A组的血细胞比容显着降低（p <0.01），淋巴细胞绝对值显着降低（p <0.01），而嗜碱性粒细胞显着更高（p <0.01）。 B组记录有嗜酸性粒细胞减少和淋巴细胞减少（p <0.01）。肝硬化中血细胞比容值和淋巴细胞的减少以及嗜碱性粒细胞的增加是显着的。血细胞比容和白细胞配方是确定绵羊肝感染的重要诊断参数。

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