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Civilian exposure to munitions-specific carcinogens and resulting cancer risks for civilians on the Puerto Rican island of Vieques following military exercises from 1947 to 1998

机译:1947年至1998年进行军事演习后,平民暴露于弹药特有的致癌物,并对波多黎各别克斯岛的平民造成平民患癌的风险

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Estimation of legacy public health risks from munitions residues near or at former military test ranges has for the past decades been a challenge to health authorities. Parts of the island of Vieques (PR) were for six decades used for military training, and these are now declared as a Superfund site. ATSDR has conducted site assessments there and found no cause for public health concerns. The reports and findings of ATSDR have since been heavily contested and disputed. This paper provides a case study on cancer risk screening of munitions-specific carcinogens for the full period of military training on Vieques. Added cancer risks and Margins of Exposure for the different carcinogens for each year were derived. We found that there is a potential for cancer risk concern related to BaP exposures. Furthermore, there were health risks from TNT exposures. The primary exposure route of these compounds was oral. The period 1992–1997 showed a significantly elevated lung and bronchus cancer incidence rate in Vieques compared to Puerto Rico mainland mainly among women?50?yr and men 50–64?yr. These correlate with high munitions exposures in the period 1977–1984.
机译:在过去的几十年中,根据接近或处于前军事试验场的弹药残留物估算遗留的公共健康风险一直是卫生当局的挑战。别克斯岛(PR)的部分地区用于军事训练已有六十年之久,现在被宣布为超级基金所在地。美国毒物与疾病登记署已经在那里进行了现场评估,没有发现引起公众健康担忧的原因。自那时以来,美国毒物与疾病登记署的报告和调查结果遭到了激烈的争论和争议。本文提供了一个案例研究,以对弹药专用军事训练的整个时期进行针对弹药特定致癌物的癌症风险筛查。得出了增加的癌症风险和每年不同致癌物的暴露裕度。我们发现与BaP暴露相关的潜在癌症风险隐患。此外,TNT暴露也存在健康风险。这些化合物的主要暴露途径是口服。 1992-1997年期间,与波多黎各大陆相比,Vieques的Vieques肺癌和支气管癌发病率显着升高,主要发生在50岁以下的女性和50-64岁的男性中。这些与1977-1984年期间的高弹药暴露有关。

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