...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Global Veterinaria >Evaluation of the Sedative, Analgesic, Physiological and Haematological Effects of Intravenous Detomidine, Detomidine-Butorphanol, Romifidine and Romifidine-Butorphanol in Baladi Goats
【24h】

Evaluation of the Sedative, Analgesic, Physiological and Haematological Effects of Intravenous Detomidine, Detomidine-Butorphanol, Romifidine and Romifidine-Butorphanol in Baladi Goats

机译：评价巴拉迪山羊静脉注射地托米定，地托米丁-丁二酚，罗米替丁和罗米替丁-丁二酚的镇静，镇痛，生理和血液学作用

获取原文
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

The present study was aimed to clarify and determine the sedative and analgesic effects ofintravenous injection of detomidine, detomidine-butrophanol, romifidine and romifidine-butorphanol inEgyptian Baladi goats and to evaluate the most efficient treatment regimen for induction of sedation andanalgesia with the least adverse effects on clinicophysiological and hematological parameters. Six baladi goats,three males and three females weighing 25-35 kg were studied in prospective randomized experimentalanaesthetic trial. Four intravenous treatments of detomidine, detomidine-butorphanol, romifidine and romifidinebutorphanolwere administered to each goat using: 0.04 mg/kg body weight detomidine, 0.04 mg/kg body weightdetomidine plus 0.03 mg/kg body weight butorphanol, 0.05 mg/kg body weight romifidine and 0.03 mg/kg bodyweight romifidine plus 0.05 mg/kg body weight butorphanol. The pulse rate, respiratory rate, rectal temperature,sedation, analgesia, ataxia, hemoglobin, packed cell volume percentage, differential leukocytic count, serumglucose, creatinine, urea, Aspartate aminotransferase and Alanine aminotransferase were evaluated. Markedsedation and complete analgesia was observed after detomidine-butorphanol and romifidine-butorphanolinjections. Frequent urination and obvious watery salivation with tympany were observed in all treated goats.A significant reduction in pulse rate was observed in all goats compared to baseline value (p<0.05). Changesin clinicophysiological and haematological parameters were transient with no obvious systemic effects.Intravenous injection of 0.04 mg/kg body weight detomidine combined with 0.03 mg/kg body weightbutorphanol or intravenous injection of 0.05 mg/kg body weight romifidine combined with 0.03 mg/kg bodyweight butorphanol showed a prolonged marked sedation and complete analgesia in Baladi goats thanintravenous injection of detomidine or romifidine alone. The combination of butorphanol with detomidine orromifidine was induced bradycardia, which within acceptable value. The adverse effects on clinicophysiologicaland haematological values were mild, transient and within the physiological limits.
机译：本研究旨在阐明和确定静脉注射去毒定，去毒定-丁啡烷，romifidine和romifidine-butorphanol在埃及Baladi山羊中的镇静和镇痛作用，并评估诱导镇静和镇痛效果最有效的治疗方案，对副作用的影响最小临床生理和血液学参数。在前瞻性随机实验麻醉试验中研究了六头巴拉迪山羊，三头雄性和三头雌性，体重在25-35 kg之间。对每只山羊分别给予了十种托咪定，全美托咪定-布托啡诺，romifidine和romifidinebutorphanol的四种静脉内治疗方法，使用量为：0.04 mg / kg体重的托托咪定，0.04 mg / kg的体重的托托咪定加0.03 mg / kg的体重布托啡诺，0.05 mg / kg的体重的romifidine和0.03 mg / kg体重的romifidine加0.05 mg / kg体重的布托啡诺。评估了脉搏率，呼吸频率，直肠温度，镇静，镇痛，共济失调，血红蛋白，细胞堆积体积百分比，白细胞计数差异，血清葡萄糖，肌酐，尿素，天冬氨酸转氨酶和丙氨酸转氨酶。注射脱托咪定-丁吗啡醇和romifidine-butorphanolinolin后镇静和完全镇痛。在所有处理过的山羊中都观察到小便频繁，并出现明显的流涎水，与基准值相比，所有山羊的脉搏率均显着降低（p <0.05）。临床生理学和血液学参数的变化是短暂的，没有明显的全身作用。静脉注射0.04 mg / kg体重的托托咪定联合0.03 mg / kg体重的布托啡诺或静脉注射0.05 mg / kg体重的罗米替丁与0.03 mg / kg体重的布托啡诺与单独静脉注射地托米定或罗米替丁相比，巴拉迪山羊具有更长的镇静作用和完全的镇痛作用。丁啡尼诺与托托咪定奥洛米定的组合引起心动过缓，在可接受的范围内。对临床生理和血液学值的不利影响是轻微的，短暂的并且在生理范围内。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号