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Advanced small cell carcinoma of the cervix – Successful treatment with concurrent etoposide and cisplatin chemotherapy and extended field radiation: A case report and discussion

机译:子宫颈晚期小细胞癌–依托泊苷和顺铂联合化疗和扩大视野放疗的成功治疗:一例病例和讨论

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The purpose of this article is to present a case of successful treatment of a patient with stage IVB small cell carcinoma of the cervix (SCCC) who was treated with concurrent chemoradiotherapy (CCRT) consisting of etoposide/cisplatin (EP) chemotherapy, external beam radiation therapy (EBRT), and brachytherapy. The patient has since remained without evidence of disease for nearly six years. This report reviews and summarizes the existing case literature on SCCC. Highlights ? Locally advanced small cell carcinoma of the cervix is an aggressive malignancy. ? Recommended treatment is concurrent chemoradiation with adjuvant chemotherapy. ? At least 5cycles of cisplatin and etoposide chemotherapy should be utilized. ? Radiation therapy must include external beam radiation therapy and brachytherapy. ? Use of prophylactic cranial irradiation is not supported by existing literature.
机译:本文的目的是介绍一个成功治疗患有IVB期宫颈小细胞癌(SCCC)的患者的案例,该患者接受了同时化疗,依托泊苷/顺铂(EP)化疗,外部束放射治疗治疗(EBRT)和近距离放射治疗。此后近六年来,患者一直没有疾病迹象。本报告回顾并总结了有关SCCC的现有案例。强调 ?子宫颈局部晚期小细胞癌是侵袭性恶性肿瘤。 ?推荐的治疗方法是同时放化疗和辅助化疗。 ?至少应使用5个周期的顺铂和依托泊苷化疗。 ?放射治疗必须包括外部束放射治疗和近距离放射治疗。 ?现有文献不支持使用预防性颅脑照射。

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