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Fertility sparing management of large cell neuroendocrine tumour of cervix: A case report & review of literature

机译:子宫颈大细胞神经内分泌肿瘤的保留生育管理:一例病例并文献复习

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Large cell neuroendocrine cervical carcinoma (LCNEC) is a rare and aggressive cancer that tends to spread and recur early despite intensive multimodal treatment. Conventional treatment strategies for early stage neuroendocrine tumour (NET) include radical hysterectomy followed by adjuvant chemotherapy. There are only 2 reported cases of fertility sparing treatment for NET. We report on the first case of successful conception and delivery at term following radical trachelectomy for early stage LCNEC. Highlights ? First reported case of delivery at term following radical trachelectomy for LCNEC ? 3 year recurrence free survival following radical trachelectomy in LCNEC ? Continue data collection on both oncologic and fertility outcomes in LCNEC.
机译:大细胞神经内分泌宫颈癌(LCNEC)是一种罕见且具有侵略性的癌症,尽管进行了密集的多式联运治疗,仍倾向于早期扩散和复发。早期神经内分泌肿瘤(NET)的常规治疗策略包括根治性子宫切除术,然后进行辅助化疗。 NET仅保留生育的2例报道。我们报道了早期LCNEC根治性气管切除术后足月成功分娩和成功分娩的第一例病例。强调 ? LCNEC根治性气管切除术后足月分娩的第一例报道? LCNEC根治性气管切除术后3年无复发生存?继续收集有关LCNEC中肿瘤和生育结果的数据。

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