...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Gut and Liver >Prevalence and Implications of Bone Marrow Involvement in Patients with Gastric Mucosa-Associated Lymphoid Tissue Lymphoma
【24h】

Prevalence and Implications of Bone Marrow Involvement in Patients with Gastric Mucosa-Associated Lymphoid Tissue Lymphoma

机译：胃黏膜相关淋巴样组织淋巴瘤患者骨髓累及的发生率及其意义

获取原文
   

获取外文期刊封面封底 >>

       
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Background/Aims Mucosa-associated lymphoid tissue (MALT) lymphoma of the stomach is an uncommon disease. Bone marrow involvement is reported even in patients with only a mucosal lesion. We evaluated the prevalence and risk factors of marrow involvement and its implications for diagnosis and treatment. Methods In total, 132 patients who were diagnosed with gastric MALT lymphoma at the National Cancer Center in Korea between January 2001 and December 2016 were enrolled in the study. The patient data were collected and analyzed retrospectively. Results Of the 132 patients, 47 (35.6%) were male, with a median age of 52 years (range, 17 to 81 years). The median follow-up duration was 48.8 months (range, 0.5 to 169.9 months). Helicobacter pylori infection was detected in 82 patients (62.1%). Most patients (80.3%) had stage IE1 according to the modified Ann Arbor staging system. Ninety-two patients underwent bone marrow evaluation, and four patients (4.3%) had marrow involvement. Of these patients, one presented with abdominal lymph node involvement, while the other three had stage IE1 disease if marrow involvement was disregarded. All three patients had no significant symptoms and were monitored after local treatment without evidence of disease aggravation. Conclusions Bone marrow involvement was found in 4.3% of the patients with gastric MALT lymphoma. Bone marrow examination may be deferred because marrow involvement does not change the treatment options or outcome in gastric MALT lymphoma confined to the stomach wall.
机译：背景/目的胃黏膜相关淋巴样组织（MALT）淋巴瘤是一种罕见的疾病。据报道，即使只有粘膜病变的患者也有骨髓受累。我们评估了骨髓受累的患病率和危险因素及其对诊断和治疗的意义。方法收集2001年1月至2016年12月在韩国国家癌症中心诊断为胃MALT淋巴瘤的132例患者作为研究对象。收集患者数据并进行回顾性分析。结果132例患者中，男性47例（35.6％），中位年龄52岁（范围17至81岁）。中位随访时间为48.8个月（范围0.5至169.9个月）。在82例患者中检测到幽门螺杆菌感染（62.1％）。根据改良的Ann Arbor分期系统，大多数患者（80.3％）患有IE1期。有92例患者接受了骨髓评估，其中4例（4.3％）患有骨髓侵犯。在这些患者中，如果不考虑骨髓受累，则其中一位表现为腹部淋巴结受累，而其他三位则为IE1期疾病。所有三名患者均无明显症状，并在局部治疗后进行了监测，没有发现病情恶化的迹象。结论4.3％的胃MALT淋巴瘤患者发现骨髓受累。骨髓检查可能会推迟，因为骨髓受累不会改变局限于胃壁的胃MALT淋巴瘤的治疗选择或结局。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号