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首页> 外文期刊>eNeurologicalSci >Income in midlife and dementia related mortality over three decades: A Norwegian prospective study
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Income in midlife and dementia related mortality over three decades: A Norwegian prospective study

机译：挪威一项前瞻性研究显示，过去三十年来中年和痴呆相关死亡率的收入

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Studies on midlife income and dementia are scarce, and our main aim was to investigate midlife with later risk of dementia related mortality, adjusting for education and dementia related risk factors. The study population consisted of Norwegian men, aged 40–59years in 1980 at income assessment, which participated in Norwegian health examination studies in the period 1980–2002 where risk factors such as cholesterol level, hypertension, smoking, cardiovascular disease, and diabetes were assessed. Dementia related mortality was defined as a dementia diagnosis on the death certificate until 2012. Cox regression was used. The study included 45,944 participants and 1062 dementia related deaths. There was no association between midlife income and dementia mortality risk (HR=1.04, 95% confidence interval (CI) 0.85, 1.28 for the lowest fifth of income compared to those in the highest fifth). For total mortality, there was a strong inverse association with income (HR=1.61, 95% CI 1.53, 1.69), which was attenuated when adjusting for education and risk factors, but still significant (HR=1.27, 95% CI 1.20, 1.34). Lower educational attainment was significantly associated with increased dementia mortality risk, also after adjustment for income and other known risk factors (HR=1.30, 95% CI 1.03, 1.64 comparing low versus high education). Midlife income was not associated with dementia related mortality, but low education was independently linked to increased risk of dementia related mortality. Our results support the cognitive reserve hypothesis suggesting that mental activity and not material resources are related to dementia related mortality.
机译：关于中年收入和痴呆症的研究很少，我们的主要目的是研究中年以后有与痴呆症相关的死亡风险，并根据教育程度和与痴呆症相关的危险因素进行调整。研究人群包括1980年收入评估时年龄在40-59岁的挪威男性，他们参加了1980-2002年的挪威健康检查研究，评估了胆固醇，高血压，吸烟，心血管疾病和糖尿病等危险因素。与痴呆有关的死亡率被定义为直到2012年的死亡证明上的痴呆诊断。使用Cox回归。该研究包括45,944名参与者和1062例与痴呆相关的死亡。中年收入与痴呆死亡率风险之间没有关联（收入最低的五分之一与收入最高的五分之一相比，HR = 1.04，95％置信区间（CI）0.85，1.28）。对于总死亡率，与收入之间存在强烈的负相关关系（HR = 1.61，95％CI 1.53，1.69），但在调整教育和危险因素后衰减了，但仍然很显着（HR = 1.27，95％CI 1.20，1.34） ）。较低的教育程度与痴呆症死亡率风险显着相关，而且在调整收入和其他已知风险因素后也是如此（HR = 1.30，95％CI 1.03，1.64低教育与高教育相比）。中年收入与痴呆症相关的死亡率无关，但是低学历与痴呆症相关的死亡风险增加独立相关。我们的结果支持认知储备假说，表明精神活动而非物质资源与痴呆相关的死亡率有关。

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