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Maternal and Fetal Outcomes Among Pregnant Women with Immune Thrombocytopenic Purpura

机译:免疫性血小板减少性紫癜孕妇的母婴结局

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OBJECTIVE: We aimed to report six pregnant women with immune thrombocytopenic purpura (ITP) followed?and delivered at our clinic. STUDY DESIGN: This retrospective study was concluded at Dicle University, School of Medicine,?Department of Obstetrics and Gynecology, between January 2008 and December 2008. The cases with?ITP were referred from the outside centers to our clinic. RESULTS: The mean platelet count of the cases were 70.9 K/UL (18.1-107). The mean age of the cases?were 29.4 (20-39), gravidy 3.6 (1-7), and parity 2.6 (0-6). The cases had ITP diagnose before pregnancy,?4 (66.6 %) of the cases had term pregnancy and spontaneous labor, 2 (33.4%) preeclampsia and?preterm labor. We induced the labor of these two cases with preeclampsia and delivered vaginally. The other 3 cases had also delivered vaginally, but one of the cases had fetal distress during labor and had?cesarean delivery. The babies were healthy, with mean birth weight of 2810 g (1900-3100), 1 minute?Apgar score 5 (3-7) and 5 minute 6.6 (5-9). We had transfused 1 unite of trombocyst apheresis solution?to one of the case. The cases discharged from the hospital without any complication and day 2-4 days (2.8 days). CONCLUSION: ITP in pregnancy can be a complex and a challenging disease. Mothers with ITP require?monitoring during pregnancy and may require intervention with agents to raise the platelet count.?With a multidisciplinary approach including obstetrician, hematologist and pediatrician good outcomes?can be taken for mother and fetus.
机译:目的:我们的目标是报告六名患有免疫性血小板减少性紫癜(ITP)并随后在我们诊所分娩的孕妇。研究设计:这项回顾性研究于2008年1月至2008年12月在Dicle大学医学部妇产科进行了总结。ITP病例从外部中心转诊至我们的诊所。结果:该病例的平均血小板计数为70.9 K / UL(18.1-107)。病例的平均年龄为29.4(20-39),妊娠3.6(1-7)和胎次2.6(0-6)。妊娠前已确诊ITP的病例中,有4例(66.6%)具有足月妊娠和自然分娩,2例(33.4%)先兆子痫和早产。我们在子痫前期引起这两个病例的分娩并阴道分娩。另外3例也经阴道分娩,但其中1例在分娩时有胎儿窘迫并进行了剖宫产。婴儿健康,平均出生体重为2810 g(1900-3100),1分钟Apgar得分5(3-7),5分钟6.6(5-9)。我们向其中一种病例输注了1个单位的trombocyst单采血液浸液。病例出院无任何并发症,每天2-4天(2.8天)。结论:妊娠ITP可能是一种复杂且具有挑战性的疾病。患有ITP的母亲在怀孕期间需要进行监测,并可能需要干预以增加血小板计数。采用多学科方法,包括产科医生,血液科医生和儿科医生,可以为母亲和胎儿采取良好的预后措施。

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