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Concomitant infections of Plasmodium falciparum and Wuchereria bancrofti on the Kenyan coast

机译:肯尼亚沿海地区的恶性疟原虫和班氏疟原虫同时感染

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Background Anopheles gambiae s.l. and An. funestus are important vectors of malaria and bancroftian filariasis, which occur as co-endemic infections along the Kenyan Coast. However, little is known about the occurrence and prevalence of concomitant infections of the two diseases in mosquito and human populations in these areas. This study reports the prevalence of concomitant infections of Plasmodium falciparum and Wuchereria bancrofti in mosquito and human populations in Jilore and Shakahola villages in Malindi, Kenya. Methods Mosquitoes were sampled inside houses by pyrethrum spray sheet collection (PSC) while blood samples were collected by finger prick technique at the end of entomological survey. Results A total of 1,979 female Anopheles mosquitoes comprising of 1,919 Anopheles gambiae s.l and 60 An. funestus were collected. Concomitant infections of P. falciparum sporozoites and filarial worms occurred in 1.1% and 1.6% of An. gambiae s.l collected in Jilore and Shakahola villages respectively. Wuchereria-infected mosquitoes had higher sporozoite rates compared to non-infected mosquitoes, but multiple infections appeared to reduce mosquito survivorship making transmission of such infections rare. None of the persons examined in Shakahola (n = 107) had coinfections of the two parasites, whereas in Jilore (n = 94), out of the 4.3% of individuals harbouring both parasites, 1.2% had P. falciparum gametocytes and microfilariae and could potentially infect the mosquito with both parasites simultaneously. Conclusion Concerted efforts should be made to integrate the control of malaria and bancroftian filariasis in areas where they co-exist.
机译:背景冈比亚按蚊S.l.和。 funestus是疟疾和bancroftian丝虫病的重要媒介,它们是肯尼亚海岸沿线的地方性感染。然而,对于在这些地区的蚊子和人群中两种疾病的伴随感染的发生和流行,人们知之甚少。这项研究报告了肯尼亚马林迪Jilore和Shakahola村的蚊子和人群中恶性疟原虫和Bancherft疟原虫的同时感染情况。方法在昆虫学调查结束时,通过除虫菊喷雾片收集(PSC)在房屋内采集蚊子,并用手指刺技术采集血液。结果总共有1,979只雌性按蚊,其中包括1,919个冈比亚按蚊s.l和60个按蚊。收集了真菌。恶性疟原虫子孢子和丝虫的同时感染发生在An的1.1%和1.6%。冈比亚s.l分别收集在Jilore和Shakahola村庄。与未感染的蚊子相比,感染乌氏杆菌的蚊子的子孢子发生率更高,但是多次感染似乎降低了蚊子的生存率,因此这种感染的传播很少。在Shakahola(n = 107)接受检查的人中,没有一个人同时感染了这两种寄生虫,而在Jilore(n = 94)中,在同时携带这两种寄生虫的4.3%的个体中,有1.2%的人患有恶性疟原虫配子体和微丝aria,并且可以可能同时感染两种寄生虫。结论应该共同努力,在其共存的地区整合对疟疾和班克罗夫特丝虫病的控制。

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