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首页> 外文期刊>Filaria journal >The geographical distribution of lymphatic filariasis infection in Malawi
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The geographical distribution of lymphatic filariasis infection in Malawi

机译：马拉维淋巴丝虫病感染的地理分布

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Mapping distribution of lymphatic filariasis (LF) is a prerequisite for planning national elimination programmes. Results from a nation wide mapping survey for lymphatic filariasis (LF) in Malawi are presented. Thirty-five villages were sampled from 23 districts excluding three districts (Karonga, Chikwawa and Nsanje) that had already been mapped and Likoma, an Island, where access was not possible in the time frame of the survey. Antigenaemia prevalence [based on immunochromatographic card tests (ICT)] ranged from 0% to 35.9%. Villages from the western side of the country and distant from the lake tended to be of lower prevalence. The exception was a village in Mchinji district on the Malawi-Zambia border where a prevalence of 18.2% was found. In contrast villages from lake shore districts [Salima, Mangochi, Balaka and Ntcheu (Bwanje valley)] and Phalombe had prevalences of over 20%. A national map is developed which incorporates data from surveys in Karonga, Chikwawa and Nsanje districts, carried out in 2000. There is a marked decline in prevalence with increasing altitude. Further analysis revealed a strong negative correlation (R2 = 0.7 p < 0.001) between altitude and prevalence. These results suggest that the lake shore, Phalombe plain and the lower Shire valley will be priority areas for the Malawi LF elimination programme. Implications of these findings as regards implementing a national LF elimination programme in Malawi are discussed.
机译：绘制淋巴丝虫病分布图是规划国家消灭计划的先决条件。本文介绍了马拉维全国范围内的淋巴丝虫病（LF）分布图调查结果。从23个地区中抽取了35个村庄，但不包括已绘制地图的三个地区（卡隆加，奇瓦瓦和尼桑杰）和岛屿利科马，在调查的时间范围内无法访问。抗原血症发生率[基于免疫色谱卡测试（ICT）]范围为0％至35.9％。该国西部和远离湖泊的村庄的患病率较低。唯一的例外是马拉维-赞比亚边境Mchinji地区的一个村庄，该地区的患病率为18.2％。相比之下，来自湖岸地区的村庄[萨利玛（Salima），曼戈奇（Mangochi），巴拉卡（Balaka）和恩奇（Ntcheu）（布涅（Bwanje）山谷）和法隆比（Phalombe）的患病率超过20％。绘制了一张全国地图，其中包含了2000年在Karonga，Chikwawa和Nsanje地区进行的调查数据。随着海拔的升高，流行率明显下降。进一步的分析显示，海拔高度与患病率之间存在很强的负相关性（R2 = 0.7 p <0.001）。这些结果表明，湖岸，Phalombe平原和夏尔河谷下游将成为马拉维LF消除计划的重点地区。讨论了这些发现对在马拉维实施国家LF消除计划的影响。

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