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首页> 外文期刊>Fisheries and Aquatic Sciences >The Growth, Innate Immunity and Protection against H2O2-Induced Oxidative Damage of a Chitosan-Coated Diet in the Olive Flounder Paralichthys olivaceus
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The Growth, Innate Immunity and Protection against H2O2-Induced Oxidative Damage of a Chitosan-Coated Diet in the Olive Flounder Paralichthys olivaceus

机译：橄榄比目鱼Paraliichthys olivaceus壳聚糖包衣饮食的生长，天然免疫和对H 2 O 2 诱导的氧化损伤的防护

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We demonstrate enhanced growth, innate immunity and protection against hydrogen peroxide ( )-induced protein oxidation and cellular DNA damage in olive flounder Paralichthys olivaceus fed a chitosan-coated moist pallet (MP) diet. A chitosan-based biopolymer coated MP as the experimental diet and a non-coated MP (control) was fed to olive flounder fish. Growth, including the average weight gain (g/fish), weight gain (%) and feed intake (g) of the fish group fed a chitosan-coated MP diet increased significantly. The survival rate was reported as 100% throughout the experimental period. Immunological parameters indicated higher mucus lysozyme activity and significantly higher fish skin mucus total protein content was observed in fish fed the chitosan-coated MP diet compared to the control. A blood plasma analysis revealed attenuation of cellular DNA and protein oxidative damage caused by -induced oxidative stress in the fish fed the chitosan-coated MP diet compared to the control group. Moreover, blood serum biochemical analysis revealed health-promoting effects, including significantly higher hemoglobin and total cholesterol levels in the fish fed the chitosan-coated MP diet compared to the control group. In conclusion, growth, innate immunity and protection against oxidative stresses were improved by feeding of the chitosan-coated MP diet to olive flounder reared in aquaculture.
机译：我们证明了在喂有壳聚糖包衣的湿托盘（MP）饮食的橄榄比目鱼（Oliparaeus olivaceus）中，生长的增强，先天免疫力和对过氧化氢（）诱导的蛋白质氧化和细胞DNA损伤的保护作用。将基于壳聚糖的生物聚合物包衣的MP作为实验饮食，将未包衣的MP（对照）喂食比目鱼。饲喂壳聚糖包衣的MP饲料的鱼群的生长，包括平均体重增加（克/鱼），体重增加（％）和饲料摄入量（g），显着增加。据报道，整个实验期间的存活率为100％。免疫学参数表明，饲喂壳聚糖包衣的MP饲料的鱼与对照组相比，粘液溶菌酶活性更高，鱼皮粘液总蛋白含量也明显更高。血浆分析显示，与对照组相比，喂食了脱乙酰壳多糖包衣的MP饲料的鱼，由于诱导的氧化应激引起的细胞DNA和蛋白质氧化损伤的减弱。此外，血清生化分析显示出健康促进作用，包括与对照组相比，喂食脱乙酰壳多糖涂层MP饮食的鱼的血红蛋白和总胆固醇水平明显更高。总之，通过将壳聚糖包衣的MP日粮饲喂水产养殖中饲养的比目鱼，可以提高生长，先天免疫力和抗氧化应激能力。

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