• 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Frontiers in Endocrinology >Browning and Graying: Novel Transcriptional Regulators of Brown and Beige Fat Tissues and Aging
【24h】

Browning and Graying: Novel Transcriptional Regulators of Brown and Beige Fat Tissues and Aging

机译：褐变和泛灰：棕色和米色脂肪组织和衰老的新型转录调节因子

获取原文
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Obesity represents a major risk factor for the development of a number of metabolic disorders, including cardiovascular disease and type 2 diabetes. Since the discovery that brown and beige fat cells exist in adult humans and contribute to energy expenditure, increasing interest has been devoted to the understanding of the molecular switches turning on calorie utilization. It has been reported that the ability of thermogenic tissues to burn energy declines during aging, possibly contributing to the development of metabolic dysfunction late in life. This review will focus on the recently identified transcriptional modulators of brown and beige cells and will discuss the potential impact of some of these thermogenic factors on age-associated metabolic disorders.
机译：肥胖是许多新陈代谢疾病发展的主要危险因素，包括心血管疾病和2型糖尿病。自从发现棕色和米色的脂肪细胞存在于成年人中并促进能量消耗以来，人们对提高卡路里利用的分子开关的兴趣日益浓厚。据报道，生热组织燃烧能量的能力在衰老过程中下降，这可能导致生命后期代谢功能障碍的发展。这项审查将侧重于最近确定的棕色和米色细胞的转录调节剂，并将讨论其中一些产热因子对与年龄相关的代谢紊乱的潜在影响。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号