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首页> 外文期刊>Fisheries science >Evaluation of antioxidant properties and biofunctions of polar, nonpolar, and water-soluble fractions extracted from gonad and body wall of the sea urchin Tripneustes gratilla
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Evaluation of antioxidant properties and biofunctions of polar, nonpolar, and water-soluble fractions extracted from gonad and body wall of the sea urchin Tripneustes gratilla

机译：从海胆的性腺和体壁提取的极性，非极性和水溶性馏分的抗氧化性能和生物功能的评估

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This study was performed to compare the various bioactivities of water-soluble, polar, and nonpolar extracts from the edible part (gonad) and waste (body wall) of the sea urchin Tripneustes gratilla. During antioxidant activity screening, these three extracts from both gonad and body wall showed various antioxidant activities in different tests. During human skin fibroblast (CCD966SK) viability and collagen screening, only water-soluble and polar extracts from gonad and body wall were observed to promote cell viability, while the water-soluble gonad extract promoted the collagen-generating activity of CCD966SK cells. The water-soluble and polar extracts from gonad and body wall showed proliferative activity towards different cell types. In contrast, the nonpolar extracts of gonad and body wall exerted antiproliferative effects on most tumor cells. These results indicate that the bioactivities of sea urchin extracts depend on the part of the urchin that the extract was taken from as well as the extraction method used.
机译：进行这项研究是为了比较海胆Tripneustes gratilla的可食用部分（性腺）和废物（体壁）中的水溶性，极性和非极性提取物的各种生物活性。在抗氧化活性筛选过程中，性腺和体壁的这三种提取物在不同的测试中均显示出多种抗氧化活性。在人类皮肤成纤维细胞（CCD966SK）的活力和胶原蛋白筛选过程中，仅观察到性腺和体壁的水溶性和极性提取物可促进细胞活力，而水溶性性腺提取物可促进CCD966SK细胞的胶原生成活性。性腺和体壁的水溶性和极性提取物对不同细胞类型具有增殖活性。相反，性腺和体壁的非极性提取物对大多数肿瘤细胞具有抗增殖作用。这些结果表明，海胆提取物的生物活性取决于提取该海胆的部分以及所用的提取方法。

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