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首页> 外文期刊>Frontiers in Public Health >Lassa Fever 2016 Outbreak in Plateau State, Nigeriaa??The Changing Epidemiology and Clinical Presentation
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Lassa Fever 2016 Outbreak in Plateau State, Nigeriaa??The Changing Epidemiology and Clinical Presentation

机译：尼日利亚高原州拉萨热2016年爆发-流行病学和临床表现的变化

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Lassa fever (LF) outbreaks in Nigeria mostly occur in rural areas and during the dry season, peaking between December through February. Fever is a cardinal presenting feature among the myriad manifestations of LF. Thirty four patients with clinical diagnosis of LF were analyzed. However, only 11 (32%) LASV infections were confirmed by RT-PCR. The 2016 LF outbreak showed a preferential urban occurrence and a high case fatality. Fever (≥38°C) was not detected in over a fourth of the patients at the time of examination. Bleeding diathesis was the most common presentation while abdominal pain and headache were present in more than half of the confirmed cases. Changes in the geographical distribution and clinical presentation may have implications for disease control efforts and the risk of transmission, both locally and internationally. In order to guide interventions, public health authorities should be aware that the epidemic patterns may be changing.
机译：尼日利亚的拉萨热（LF）暴发主要发生在农村地区和干旱季节，在12月至2月之间达到峰值。发烧是LF多种表现形式中的主要表现。分析了34例LF的临床诊断。然而，通过RT-PCR仅确认了11例（32％）LASV感染。 2016年的LF暴发显示出市区优先发生和高致死率。在检查时，超过四分之一的患者未发现发烧（≥38°C）。血脂过多是最常见的表现，而在一半以上的确诊病例中出现腹痛和头痛。地理分布和临床表现的变化可能对疾病控制工作和本地和国际上的传播风险有影响。为了指导干预措施，公共卫生当局应意识到流行方式可能正在发生变化。

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