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首页> 外文期刊>Frontiers in Public Health >Steroid Hormones and Their Action in Women's Brains: The Importance of Hormonal Balance
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Steroid Hormones and Their Action in Women's Brains: The Importance of Hormonal Balance

机译：类固醇激素及其在女性大脑中的作用：荷尔蒙平衡的重要性

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摘要

Sex hormones significantly impact women's lives. Throughout the different stages of life, from menarche to menopause and all stages in between, women experience dramatic fluctuations in the levels of progesterone and estradiol, among other hormones. These fluctuations affect the body as a whole, including the central nervous system (CNS). In the CNS, sex hormones act via steroid receptors. They also have an effect on different neurotransmitters such as GABA, serotonin, dopamine, and glutamate. Additionally, studies show that sex hormones and their metabolites influence brain areas that regulate mood, behavior, and cognitive abilities. This review emphasizes the benefits a proper hormonal balance during the different stages of life has in the CNS. To achieve this goal, it is essential that hormone levels are evaluated considering a woman's age and ovulatory status, so that a correct diagnosis and treatment can be made. Knowledge of steroid hormone activity in the brain will give women and health providers an important tool for improving their health and well-being.
机译：性激素显着影响女性的生活。在从初潮到更年期以及介于两者之间的各个阶段的整个生命阶段中，女性的孕激素和雌二醇以及其他激素的水平都会发生剧烈波动。这些波动会影响整个身体，包括中枢神经系统（CNS）。在中枢神经系统中，性激素通过类固醇受体起作用。它们还对不同的神经递质（例如GABA，5-羟色胺，多巴胺和谷氨酸）有影响。此外，研究表明，性激素及其代谢产物会影响调节情绪，行为和认知能力的大脑区域。这篇综述强调了中枢神经系统在生命的不同阶段适当的荷尔蒙平衡所带来的好处。为了实现这一目标，必须根据女性的年龄和排卵状况来评估激素水平，以便做出正确的诊断和治疗。大脑中类固醇激素活性的知识将为妇女和保健人员提供改善其健康状况的重要工具。

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