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首页> 外文期刊>Frontiers in Public Health >A Presumptive Case of Human Rabies: A Rare Survived Case in Rural Ghana
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A Presumptive Case of Human Rabies: A Rare Survived Case in Rural Ghana

机译：一个人类狂犬病的推定病例：加纳农村地区一例罕见的幸存病例

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Rabies remains endemic in Ghana and continues to pose a major public health threat to humans and animals with a nearly 100% case fatality rate in humans. We report of a presumptive case of human rabies whose survival represents a rare occurrence in rural Ghana and worldwide. Lessons from this case study provide a critically needed focus in helping improve rabies surveillance and case management in Ghana. We report of the survival of a 36-year-old man who developed clinical rabies after he was bitten by his dog, while restraining the dog with a chain. Prior to this, he did not observe any abnormal or rabid behavior in the dog. Following the bite, he did not immediately resort to hospital treatment, but rather to traditional application of herbs to the laceration he sustained after the bite. The reason given for not seeking immediate hospital treatment was that the dog was not rabid and lack of funds to seek hospital care. However, after 10 days he began to show symptoms of confusion, hydrophobia, and photophobia, consistent with rabies virus infection, and was subsequently rushed to the hospital by relatives. At the hospital, he was administered human immune tetanus immunoglobulin, diazepam, ceftriaxone, paracetamol, and intravenous fluids. No rabies vaccine was administered. Six days after commencing treatment, the patient became well, showed neither signs of confusional state, hydrophobia, nor photophobia. He was discharged home after 13 days of commencing treatment. This study provides insight on a presumptive case of human rabies that survived despite non-administration of rabies vaccine after exposure. It also exposes the weaknesses in the health and veterinary systems in rural Ghana regarding rabies surveillance and case management.
机译：狂犬病在加纳仍然很流行，继续对人类和动物构成重大的公共卫生威胁，人类的病死率接近100％。我们报告了一个人类狂犬病的推测病例，其存活率在加纳农村地区和世界范围内很少发生。该案例研究的教训非常关键，着重于帮助加纳改善狂犬病监测和病例管理。我们报道了一名36岁男子的生存情况，该男子在被狗咬伤后用链条约束该狗，但出现了临床狂犬病。在此之前，他没有观察到狗的任何异常或狂犬病行为。咬伤后，他没有立即求助于医院，而是在咬伤后持续的撕裂伤中使用了传统的草药疗法。不寻求立即住院治疗的原因是，这只狗没有狂犬病，也缺乏寻求医院护理的资金。然而，十天后，他开始表现出混乱，疏水和畏光的症状，与狂犬病病毒感染相一致，随后被亲戚赶往医院。在医院，他接受了人类免疫破伤风免疫球蛋白，地西epa，头孢曲松，扑热息痛和静脉输液。没有接种狂犬病疫苗。开始治疗六天后，患者恢复健康，未出现混乱状态，疏水性或畏光的迹象。他开始治疗13天后已出院。这项研究提供了一个关于人类狂犬病的推测病例的见解，尽管该人在暴露后仍未接种狂犬病疫苗，但仍存活下来。它还暴露了加纳农村地区在狂犬病监测和病例管理方面的卫生和兽医系统的弱点。

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