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首页> 外文期刊>Frontiers in Public Health >Are There Striking Differences in Outpatient Use of Antibiotics Between South Backa District, Serbia, and Some Scandinavian Countries?
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Are There Striking Differences in Outpatient Use of Antibiotics Between South Backa District, Serbia, and Some Scandinavian Countries?

机译：南Backa区，塞尔维亚和一些斯堪的纳维亚国家之间在门诊使用抗生素方面有显着差异吗？

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There is little published information about antibiotic utilization in outpatients in Serbia. The objective of this study was to determine the amount and structure of outpatient antibiotic use in South Backa District (SBD) in Serbia, to assess prescibing quality of antibiotics and to compare with results from Scandinavian countries. Data on the antibiotic use were collected from all private and state-owned pharmacies from January through March 2008 in SBD. Results were expressed as the number of defined daily doses/1,000 inhabitants/day. The drug utilization 90% method was also used. Penicillins were the most frequently used antibiotic subgroup in SBD (35.20%), followed by cephalosporins (19.16%) and macrolides (13.18%). Thirteen drugs accounted for 90% of total antibiotics consumption (DU90% segment). The average cost/DDD within the DU90% segment was 0.95 euros, whereas the average cost/DDD beyond the DU90% segment was 1.89 euros, indicating that less expensive antibiotics were more frequently used. High use of ampicillin, third-generation cefalosporins, co-trimoxazole, and gentamicin, will aggravate the alarming problem of resistance in Serbia. Differences in the amount and structure of antibiotic consumption between SBD and Scandinavian countries indicate the need of updated national guidelines for rational antimicrobial drug use in Serbia.
机译：关于塞尔维亚门诊病人使用抗生素的信息很少。这项研究的目的是确定塞尔维亚南Backa区（SBD）门诊使用抗生素的数量和结构，评估抗生素的处方质量，并与斯堪的纳维亚国家的结果进行比较。有关抗生素使用的数据收集自2008年1月至3月在SBD的所有私营和国有药房。结果表示为规定的日剂量/ 1,000居民/天。还使用了90％的药物利用率方法。青霉素是SBD中最常用的抗生素亚类（35.20％），其次是头孢菌素（19.16％）和大环内酯类（13.18％）。十三种药物占抗生素消费总量的90％（DU90％细分市场）。 DU90％部分的平均成本/ DDD为0.95欧元，而DU90％部分以外的平均成本/ DDD为1.89欧元，表明更便宜的抗生素得到了更广泛的使用。大量使用氨苄西林，第三代头孢菌素，复方新诺明和庆大霉素，将加剧塞尔维亚令人担忧的耐药性问题。 SBD和斯堪的纳维亚国家之间抗生素消费量和结构的差异表明，有必要更新塞尔维亚合理使用抗生素的国家指导原则。

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