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Prevalent emm Types among Invasive GAS in Europe and North America since Year 2000

机译:自2000年以来在欧洲和北美的侵入性GAS中普遍存在的emm类型

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BackgroundStreptococcus pyogenes or group A streptococcus (GAS) is an important human pathogen responsible for a broad range of infections, from uncomplicated to more severe and invasive diseases with high mortality and morbidity. Epidemiological surveillance has been crucial to detect changes in the geographical and temporal variation of the disease pattern; for this purpose the M protein gene (emm) gene typing is the most widely used genotyping method, with more than 200 emm types recognized. Molecular epidemiological data have been also used for the development of GAS M protein-based vaccines.
机译:背景化脓性链球菌或A组链球菌(GAS)是一种重要的人类病原体,可引起多种感染,从不复杂的疾病到具有高死亡率和发病率的更严重的侵入性疾病。流行病学监测对于检测疾病模式的地理和时间变化至关重要。为此,M蛋白基因(emm)基因分型是应用最广泛的基因分型方法,已识别出200多种emm类型。分子流行病学数据也已用于开发基于GAS M蛋白的疫苗。

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