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Medicinal mushroom Taiwanofungus camphoratus: A potential cure for cancer

机译:药用蘑菇台湾香樟:潜在的癌症治疗方法

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Based on traditional and folk medicine , mushrooms have been developed into anti-cancer therapeutics. In this article, a brief overview is given of the most important medical mushroom species and their specific anti-cancer functions and mechanisms. Taiwanofungus camphoratus (Antrodia cinnamomea), is a medical fungus chosen to examine the process from ethnomedicine to developing new products for the market based on scientific, analytic, and experimental evidence. The bioactive compounds have indirect effects in cancer treatment by benefiting the immune system as well as having direct cytotoxic effects on cancer cells.Taiwanofungus camphoratus is a fungus endemic to Taiwan and one of the most popular known alternative remedies for liver cancer in Taiwan. To date, more than 150 liver cancer patients have survived using T. camphoratus. The treatment has caused tumor shrinking, as well as the disappearance of a tumor altogether in some cases. The ratio between male and female patients has been nearly equal, with ages ranging between 20-79 years. The most effective candidates are those between the ages of 40-60 years.The complex mixture of bioactive compounds in natural fruit bodies is a challenge for artificial production in vitro. Particular problems in developing T. camphoratus into therapeutics for the global market are its rarity in nature and its close dependence on an endemic tree in Taiwan. These challenges can help promote new solutions which could be utilized in the future with other medical fungi.
机译:在传统和民间医学的基础上,蘑菇已发展成为抗癌疗法。在本文中,简要概述了最重要的药用蘑菇种类及其特定的抗癌功能和机制。樟脑樟木(Antrodia cinnamomea)是一种医用真菌,被选为根据科学,分析和实验证据来研究从民族药到开发面向市场的新产品的过程。该生物活性化合物通过有益于免疫系统而对癌症具有间接作用,并对癌细胞具有直接的细胞毒性作用。台湾香樟(Taiwanofungus camphoratus)是台湾特有的真菌,是台湾最流行的肝癌替代疗法之一。迄今为止,已有150多名肝癌患者使用樟脑锥虫存活。这种治疗导致肿瘤缩小,在某些情况下甚至导致肿瘤完全消失。男性和女性患者的比例几乎相等,年龄在20-79岁之间。最有效的候选药物是40-60岁之间的药物。天然果体内复杂的生物活性化合物混合物是体外人工生产的挑战。将樟脑樟脑发展为全球市场的治疗剂时,特别的问题是其天然的稀有性和对台湾特有树种的紧密依赖。这些挑战可以帮助促进新的解决方案,将来可以与其他医疗真菌一起使用。

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