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首页> 外文期刊>Macedonian Journal of Medical Sciences >Compression of the Seventh Cervical Vertebra Following C6-7 and C7-T1 Discectomy, PEEK Cage Implantation in these Intervertebral Spaces, and Management of this Complication in a Patient with Multiple Myeloma
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Compression of the Seventh Cervical Vertebra Following C6-7 and C7-T1 Discectomy, PEEK Cage Implantation in these Intervertebral Spaces, and Management of this Complication in a Patient with Multiple Myeloma

机译:C6-7和C7-T1椎间盘切除术后第七颈椎椎体受压,这些​​椎间隙中PEEK笼式植入术以及多发性骨髓瘤患者这种并发症的处理

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摘要

Patients with multiple myeloma suffer from bone pain, and spontaneous spinal and appendicular bone fractures due to osteoporosis. Osteoporosis occurs as a result of the following 2 factors: 1. Plasma cells secrete macrophage inflammatory protein-1 alpha, which induces osteoclastic activity; 2. Use of corticosteroids. The incidence of osteoporotic fractures and other complications of multiple myeloma are well described in the literature, but the management of cervical disc herniation and its associated complications has not been reported to date. Herein we present a case that we think exemplifies the management of cervical disc herniation and its complications. Consecutive multilevel cervical discectomy and placement of PEEK cages between the intervertebral cervical disc spaces may cause compression fracture of the vertebrae located between the PEEK cages in osteoporotic patients under continuous corticosteroid treatment-whether or not they have MM; therefore, we recommend use of an anterior plate to prevent this complication.
机译:多发性骨髓瘤患者患有骨痛,骨质疏松导致自发性脊柱和阑尾骨折。骨质疏松症是由以下两个因素引起的:1.浆细胞分泌巨噬细胞炎性蛋白-1α,该蛋白诱导破骨细胞活性。 2.使用皮质类固醇。文献中已经很好地描述了骨质疏松性骨折和多发性骨髓瘤其他并发症的发生率,但是迄今为止尚未报道颈椎间盘突出症的治疗及其相关并发症。在这里,我们提出一个案例,我们认为这是颈椎间盘突出症及其并发症的示例。连续皮质类固醇激素治疗的骨质疏松患者,连续多级颈椎间盘摘除术和在椎间盘颈椎间隙之间放置PEEK笼可能会导致位于PEEK笼之间的椎骨压缩性骨折;因此,我们建议使用前板以防止这种并发症。

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