A Robust and Efficient Numerical Method for RNA-Mediated Viral Dynamics

Reinharz Vladimir; Churkin Alexander; Dahari Harel; Barash Danny

首页> 外文期刊>Frontiers in Applied Mathematics and Statistics >A Robust and Efficient Numerical Method for RNA-Mediated Viral Dynamics

【24h】

A Robust and Efficient Numerical Method for RNA-Mediated Viral Dynamics

机译：RNA介导的病毒动力学的鲁棒高效数值方法

获取原文

掌桥外文数据库（机构版） >>

开具论文收录证明 >>

文献代查 >>

页面导航

摘要
著录项
相似文献
相关主题

摘要

The multiscale model of hepatitis C virus (HCV) dynamics, which includes intracellular viral RNA (vRNA) replication, has been formulated in recent years in order to provide a new conceptual framework for understanding the mechanism of action of a variety of agents for the treatment of HCV. We present a robust and efficient numerical method that belongs to the family of adaptive stepsize methods and is implicit, a Rosenbrock type method that is highly suited to solve this problem. We provide a Graphical User Interface that applies this method and is useful for simulating viral dynamics during treatment with anti-HCV agents that act against HCV on the molecular level.

机译：近年来已建立了包括细胞内病毒RNA（vRNA）复制在内的丙型肝炎病毒（HCV）动态多尺度模型，以提供一个新的概念框架，以了解各种治疗药物的作用机理。 HCV。我们提出了一种稳健而高效的数值方法，它属于自适应逐步调整方法家族，并且是隐式的，非常适合解决此问题的Rosenbrock型方法。我们提供了使用此方法的图形用户界面，可用于模拟在分子水平上抗HCV的抗HCV剂治疗过程中的病毒动力学。

著录项

来源
《Frontiers in Applied Mathematics and Statistics》 |2017年第1期|共页
作者
Reinharz Vladimir; Churkin Alexander; Dahari Harel; Barash Danny;
展开▼
作者单位

展开▼
收录信息
原文格式 PDF
正文语种
中图分类统计学;
关键词
Hepatitis C virusMultiscale modelAge-structured modelRNA-mediated viral dynamicsPartial Differential Equationsnumerical solutionRosenbrock method;

机译：丙型肝炎病毒多尺度模型年龄结构模型RNA介导的病毒动力学偏微分方程数值解Rosenbrock方法;

相似文献

外文文献
中文文献
专利

1. A robust and efficient numerical method to compute the dynamics of the rotating two-component dipolar Bose-Einstein condensates [J] . Tang Qinglin, Zhang Yong, Mauser Norbert J. Computer physics communications . 2017,第期

机译：一种稳健而有效的数值方法，以计算旋转双组分偶极Bose-Einstein冷凝物的动态
2. Discontinuous Galerkin Methods for Compressible and Incompressible Flows on Space-Time Adaptive Meshes: Toward a Novel Family of Efficient Numerical Methods for Fluid Dynamics [J] . Fambri Francesco Archives of Computational Methods in Engineering . 2020,第1期

机译：时空自适应网格上可压缩和不可压缩流的不连续Galerkin方法：面向流体动力学的新型高效数值方法
3. NUMERICAL SOLUTION OF THE NONLINEAR POISSON-BOLTZMANN EQUATION - DEVELOPING MORE ROBUST AND EFFICIENT METHODS [J] . Holst MJ., Saied F. Journal of Computational Chemistry: Organic, Inorganic, Physical, Biological . 1995,第3期

机译：非线性Poisson-Boltzmann方程的数值解 - 开发更强大的高效方法
4. Robust and efficient numerical methods for theprediction of pollutants using detailed kinetics andfluid dynamics [C] . Alessio Frassoldati, Alberto Cuoci, Tiziano Faravelli, 19th European symposium on computer aided process engineering . 2009

机译：使用详细的动力学和流体动力学预测污染物的鲁棒高效方法
5. Efficient Numerical Methods for Dislocation Dynamics Simulation. [D] . Zhao, Degang. 2010

机译：位错动力学仿真的有效数值方法。
6. A Robust and Efficient Numerical Method for RNA-Mediated Viral Dynamics [O] . Vladimir Reinharz, Alexander Churkin, Harel Dahari, -1

机译：RNA介导的病毒动力学的鲁棒高效数值方法
7. A Robust and Efficient Numerical Method for RNA-Mediated Viral Dynamics [O] . Vladimir Reinharz, Alexander Churkin, Harel Dahari, 2017

机译：RNa介导的病毒动力学的一种稳健高效的数值方法

A Robust and Efficient Numerical Method for RNA-Mediated Viral Dynamics

摘要

著录项

相似文献

相关主题

期刊订阅