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首页> 外文期刊>Materials >From Waste to Healing Biopolymers: Biomedical Applications of Bio-Collagenic Materials Extracted from Industrial Leather Residues in Wound Healing
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From Waste to Healing Biopolymers: Biomedical Applications of Bio-Collagenic Materials Extracted from Industrial Leather Residues in Wound Healing

机译：从废物到修复生物聚合物：从工业皮革残留物中提取的生物胶原材料在伤口修复中的生物医学应用

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The biomedical properties of a porous bio-collagenic polymer extracted from leather industrial waste residues have been investigated in wound healing and tissue regeneration in induced wounds in rats. Application of the pure undiluted bio-collagen to induced wounds in rats dramatically improved its healing after 7 days in terms of collagen production and wound filling as well as in the migration and differentiation of keratinocytes. The formulation tested was found to be three times more effective than the commercial reference product Catrix® (Heal Progress (HP): 8 ± 1.55 vs. 2.33 ± 0.52, p 0.001; Formation of Collagen (FC): 7.5 ± 1.05 vs. 2.17 ± 0.75, p 0.001; Regeneration of Epidermis (RE): 13.33 ± 5.11 vs. 5 ± 5.48, p 0.05).
机译：从皮革工业废渣中提取的多孔生物胶原聚合物的生物医学特性已在大鼠诱导伤口的伤口愈合和组织再生中进行了研究。将纯净的未稀释生物胶原蛋白应用于大鼠诱发的伤口，可在7天后极大地改善胶原蛋白的产生和伤口填充以及角质形成细胞的迁移和分化，从而促进其愈合。发现所测试的配方比市售参考产品Catrix ®有效三倍（治疗进度（HP）：8±1.55对2.33±0.52，p <0.001; ）：7.5±1.05 vs. 2.17±0.75，p <0.001;表皮再生（RE）：13.33±5.11 vs. 5±5.48，p <0.05）。

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