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SEM-EDX Study of the Degradation Process of Two Xenograft Materials Used in Sinus Lift Procedures

机译:窦举过程中两种异种移植材料降解过程的SEM-EDX研究

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Some studies have demonstrated that in vivo degradation processes are influenced by the material’s physico-chemical properties. The present study compares two hydroxyapatites manufactured on an industrial scale, deproteinized at low and high temperatures, and how physico-chemical properties can influence the mineral degradation process of material performance in bone biopsies retrieved six months after maxillary sinus augmentation. Residual biomaterial particles were examined by field scanning electron microscopy (SEM) and energy dispersive X-ray spectroscopy (EDX) to determine the composition and degree of degradation of the bone graft substitute material. According to the EDX analysis, the Ca/P ratio significantly lowered in the residual biomaterial (1.08 ± 0.32) compared to the initial composition (2.22 ± 0.08) for the low-temperature sintered group, which also presented high porosity, low crystallinity, low density, a large surface area, poor stability, and a high resorption rate compared to the high-temperature sintered material. This demonstrates that variations in the physico-chemical properties of bone substitute material clearly influence the degradation process. Further studies are needed to determine whether the resorption of deproteinized bone particles proceeds slowly enough to allow sufficient time for bone maturation to occur.
机译:一些研究表明,体内降解过程受材料的物理化学性质影响。本研究比较了在高温和高温下脱蛋白的两种工业规模生产的羟基磷灰石,以及理化特性如何影响上颌窦增大后六个月取回的骨活检材料的矿物降解过程。通过场扫描电子显微镜(SEM)和能量色散X射线光谱(EDX)检查残留的生物材料颗粒,以确定骨移植替代材料的组成和降解程度。根据EDX分析,与低温烧结组的初始成分(2.22±0.08)相比,残留生物材料中的Ca / P比(1.08±0.32)明显降低,这也表现出高孔隙率,低结晶度,低与高温烧结材料相比,其密度大,表面积大,稳定性差和吸收率高。这表明骨替代材料的物理化学性质的变化明显影响降解过程。需要进行进一步的研究以确定脱蛋白的骨颗粒的吸收是否进行得足够慢,以使骨骼有足够的时间成熟。

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