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首页> 外文期刊>Materials >The Efficacy of Electron Beam Irradiated Bacterial Cellulose Membranes as Compared with Collagen Membranes on Guided Bone Regeneration in Peri-Implant Bone Defects
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The Efficacy of Electron Beam Irradiated Bacterial Cellulose Membranes as Compared with Collagen Membranes on Guided Bone Regeneration in Peri-Implant Bone Defects

机译：与胶原膜相比，电子束辐照细菌纤维素膜对种植体周围骨缺损的引导性骨再生的功效。

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Bacterial cellulose (BC) is a natural polysaccharide produced by some bacteria, and consists of a linear polymer linked by β-(1,4) glycosidic bonds. BC has been developed as a material for tissue regeneration purposes. This study was conducted to evaluate the efficacy of resorbable electron beam irradiated BC membranes (EI-BCMs) for guided bone regeneration (GBR). The electron beam irradiation (EI) was introduced to control the biodegradability of BC for dental applications. EI-BCMs had higher porosity than collagen membranes (CMs), and had similar wet tensile strengths to CMs. NIH3T3 cell adhesion and proliferation on EI-BCMs were not significantly different from those on CMs ( p > 0.05). Micro-computed tomography (μCT) and histometric analysis in peri-implant dehiscence defects of beagle dogs showed that EI-BCMs were non-significantly different from CMs in terms of new bone area (NBA; %), remaining bone substitute volume (RBA; %) and bone-to-implant contact (BIC; %) ( p > 0.05). These results suggest resorbable EI-BCMs can be used as an alternative biomaterial for bone tissue regeneration.
机译：细菌纤维素（BC）是由某些细菌产生的天然多糖，由通过β-（1,4）糖苷键连接的线性聚合物组成。 BC已经被开发为用于组织再生目的的材料。进行这项研究以评估可吸收电子束辐照的BC膜（EI-BCM）对引导性骨再生（GBR）的功效。引入电子束辐照（EI）来控制BC在牙科应用中的生物降解能力。 EI-BCM的孔隙率高于胶原膜（CM），并且具有与CM相似的湿拉伸强度。 EI-BCM上的NIH3T3细胞黏附和增殖与CM上的无显着差异（p> 0.05）。微型计算机断层扫描（μCT）和比格犬组织植入裂开缺损的组织学分析表明，EI-BCM与CM的新骨面积（NBA;％），剩余骨替代量（RBA; ％）和骨与种植体的接触（BIC;％）（p> 0.05）。这些结果表明，可吸收的EI-BCM可用作骨组织再生的替代生物材料。

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