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首页> 外文期刊>Medical Journal of Shree Birendra Hospital >Factors Associated with Adherence to Antiretroviral Therapy Among People Living With HIV AIDS
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Factors Associated with Adherence to Antiretroviral Therapy Among People Living With HIV AIDS

机译：艾滋病病毒感染者坚持抗逆转录病毒疗法相关的因素

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Introduction: AIDS and STD is prioritised disease control program of Nepal. Successful treatment of HIV positive patient is fundamental to control the progression to AIDS and ART adherence is crucial for successful treatment. The objective of the study was to find out the factors associated with adherence to antiretroviral therapy among people living with HIV/AIDS. Methods: Descriptive cross sectional research design was adopted. A total of 195 people living with HIV who were above the age 18 years and taking ARV therapy for at least six months from the ART centre of Sukraraj Tropical and Infectious Disease Hospital were selected by using purposive sampling technique. Data was collected using interview technique with semi structured questionnaire. Collected data was analysed using descriptive and inferential statistics. Results: The findings showed that 91.28% of the respondents reported perfect adherence (≥95%) and 8.71% of the respondents reported non- adherence. Age (OR: 4.28; CI 1.00-18.26) and marital status (OR: 4.96; CI 1.67-14.75) were the socio-demographic factors associated with adherence to ARV therapy. Number of tablets per day (OR: 10.72; CI 1.21-94.4) and use of reminders tool (OR:11.14; CI 2.35-52.75) were the patient related factors significantly associated with the adherence to ARV therapy. Likewise, experience of no discrimination (OR 3.90; CI 1.11-13.69) and help for the intake of medicine from family members (OR 2.95; CI 1.95-9.19) were the psychosocial factors significantly associated with adherence to ARV therapy. Adherence counselling (OR 13.38; CI 2.99-59.75) and lower travelling cost (OR 3.99; CI 1.40-11.34) were the service factors significantly associated with adherence to ARV therapy. Conclusions: The prevalence of adherence found in this study was good. Help from the family members, adherence counselling and use of reminders tool for intake of medicine enhanced adherence. Whereas, side effects, alcohol use, burden of pills, experience of discrimination were the barriers for adherence to ART. For improving adherence government and as well as the hospital requires interventions which recognise these barriers.
机译：简介：艾滋病和性病是尼泊尔的重点疾病控制计划。 HIV阳性患者的成功治疗对于控制艾滋病的发展至关重要，而ART依从性对成功治疗至关重要。这项研究的目的是找出与艾滋病毒/艾滋病感染者坚持抗逆转录病毒疗法有关的因素。方法：采用描述性横断面研究设计。通过使用有针对性的抽样技术，从Sukraraj热带与传染病医院ART中心选择了总共195名18岁以上并接受ARV治疗至少六个月的HIV感染者。使用访谈技术和半结构化问卷收集数据。使用描述性和推论统计分析收集的数据。结果：调查结果显示，有91.28％的受访者表示完全遵守（≥95％），而有8.71％的受访者表示没有遵守。年龄（OR：4.28; CI 1.00-18.26）和婚姻状况（OR：4.96; CI 1.67-14.75）是与ARV治疗依从性相关的社会人口统计学因素。每天服用片剂的数量（OR：10.72; CI 1.21-94.4）和使用提醒工具（OR：11.14; CI 2.35-52.75）是与抗逆转录病毒疗法依从性显着相关的患者相关因素。同样，无歧视的经历（OR 3.90; CI 1.11-13.69）和帮助家人服用药物的帮助（OR 2.95; CI 1.95-9.19）是与坚持抗逆转录病毒疗法密切相关的社会心理因素。坚持咨询（OR 13.38; CI 2.99-59.75）和较低的差旅费用（OR 3.99; CI 1.40-11.34）是与坚持抗逆转录病毒疗法密切相关的服务因素。结论：本研究发现的依从性良好。在家庭成员的帮助下，依从性咨询和使用提醒工具来摄取药物可增强依从性。而副作用，饮酒，吃药量，歧视经历是坚持抗逆转录病毒疗法的障碍。为了提高依从性，政府和医院都需要采取干预措施来认识这些障碍。

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